ASD

GO:0051051 negative regulation of transport (211)

GeneInput weightStandardRank
GNAO1--4
CNR10.25129
YWHAB0.251107
HTR2A0.251121
GRM70.251137
ABR--160
PPP3CA--244
SOX4--250
GABBR10.251264
PDE8B--1287
CALM3--352
NF10.251372
SFRP1--387
ABCC8--1406
NEDD4L--495
PLCB4--575
G3BP2--610
SNCA--1667
NPY5R0.251725
KCNA5--1743
IL1RAPL10.251774
NOS10.251853
FBXW11--859
NRG10.251936
ADORA1--960
CALCA--1013
AKT10.2511020
CALM1--1029
APC2--1115
PKIA--1118
BMP7--1137
NPY1R0.2511190
CX3CL1--1199
IRS2--11300
ERBB3--1350
IRS1--11374
ADRA2A0.2511399
TXN--1408
EDN3--11577
RAC1--1617
AKAP5--1759
MXI1--11763
BCR--11839
GRB10--1910
CARTPT0.2511957
PFKL--2192
PSMD10--2412
GHSR0.2512467
PICALM--12597
NCS1--2628
SCAMP50.2512682
LATS1--2781
CALM2--2814
INHBB--2842
NOTCH1--12865
PDE4C--3021
KIAA0226--3048
CDK50.2513194
ARF6--3317
TRH--3416
DAB2IP--3482
FOXF1--13518
SLC18A1--3611
STIM2--3653
SERPINE2--3708
DRD20.2513749
PDE3B--3819
FGF23--13888
AKT2--13912
ACVR1C--3963
AKAP1--4078
GSK3A--4141
CRBN--4203
PXK--4240
AXIN2--14260
FLNA--14285
P2RY1--4342
DRD30.2514349
MAPK7--4384
PACSIN1--4607
CYLD--14624
SIRT4--4652
INHA--4765
NLRP30.2514959
PTGS20.2515085
BARD1--15343
PEA15--5442
NFKBIA--5569
BEST3--5665
GNAI2--5860
INSR--15872
OPRD10.2516030
ADIPOQ0.2516032
ENPP1--16091
KEAP1--6103
NR1H2--6183
CIDEA--6211
MAOB0.2516329
OXTR0.516388
SLC18A2--6423
NDFIP1--6744
GOPC--6764
SERGEF--6993
DRD40.2517021
AVPR2--17031
SLC30A1--7241
TNFSF4--7262
SFRP4--7310
IFNA2--7694
IL11--7718
KCNQ1--17724
SYTL4--7863
ADRA2C--8551
ABCG8--9041
KCNJ11--19151
GHRL0.2519242
IL10--19513
EDN1--9540
REST--9779
PKDCC--9871
ADRA2B--10119
NDFIP2--10157
CRYAA--10509
IL1B--110818
FFAR4--10968
OXT0.25111176
SFRP5--11273
TRAT1--11378
UCN2--11559
HCRT0.25111633
RHOC--11655
ITGB30.5111817
LEP0.25111864
WWP2--11885
FOXP3--112457
IL6--112695
EGF0.25112881
UACA--12955
LRSAM1--13116
MTMR2--113176
MDFI--13519
IL33--13620
UTS2R--13768
APOC2--13818
PSMD9--13911
NEDD40.25114040
ABCG5--14086
APOA2--14659
FST--14783
TNF0.25115243
INHBA--16974
YRDC--18281
EDN2--18677
APOA1--118958
SREBF1--19464
OSM--19580
NFKBIE--19710
NLRP12--19807
F2RL1--19969
EMD--120034
PLA2G10--20040
TGFB10.25120135
APOC3--20262
NFKB1--20281
EPO--20282
NFKBIL1--20431
TONSL--20639
FAM3D--20640
TNFRSF4--20689
FZD1--20775
PACSIN3--21093
MTOR--21095
SRGN--21336
TACC3--21671
MDFIC--21692
SLC9A3R1--21898
BTN2A2--21999
C5--122004
INS--122047
PKIG--22117
LIF--22134
ANXA10.5122810
NFKBIB--22875
HNF4A--122965
RHBDF1--23088
RHBDF2--23158
RSC1A1--23221
ADRB20.25123251
GNB2L1--23282
CCR2--23296
FAF1--23304
CD36--23662
APOC1--23668
ICAM1--23720
HMOX1--23938
SNAI2--123962
CD74--24030
WWTR1--24317
ANPEP--24320
THBS1--24444
PTGS1--24613
ADA0.5124751
CRYAB--124965
NR1H3--25006
CNN2--25083
DPH3--25120
STXBP3--25176
HADH--125329
IL1RN0.25125385
ITGAV--25460
ARL6IP5--25508

Network

GO:0051051

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HGNC: 4599  Ensembl: ENSG00000196277  HPRD: 04979 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRM7glutamate receptor, metabotropic 7
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRM7GRM7glutamate receptor, metabotropic 7

Troyanskaya Laboratory - Princeton University