ASD

GO:0045599 negative regulation of fat cell differentiation (25)

GeneInput weightStandardRank
LRP6--279
TRIB2--472
ZFPM2--1867
ID4--1009
SIRT1--1233
WNT10B--1517
JAG1--11704
GATA3--2376
INSIG1--2529
GATA2--13291
WNT5A--3319
WNT1--4383
AXIN1--14419
WNT3--4613
WNT3A--4747
ADIPOQ0.2516032
ENPP1--16091
IL6--112695
TNF0.25115243
TGFB10.25120135
TRIB3--20863
CCDC85B--22207
SOD2--22687
TGFB1I1--23709
WWTR1--24317

Network

GO:0045599

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
ZFPM2zinc finger protein, FOG family member 2 Entrez:23414  Ensembl: ENSG00000169946  HGNC: 16700  HPRD: 04737 
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein Entrez:3400  HGNC: 5363  HPRD: 08995 
SIRT1sirtuin 1 Entrez:23411  Ensembl: ENSG00000096717  HPRD: 08381  HGNC: 14929 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
TRIB2tribbles homolog 2 (Drosophila)
ZFPM2zinc finger protein, FOG family member 2
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
SIRT1sirtuin 1
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
TRIB2TRIB2tribbles homolog 2 (Drosophila)
ZFPM2ZFPM2zinc finger protein, FOG family member 2
ID4ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
SIRT1SIRT1sirtuin 1

Troyanskaya Laboratory - Princeton University