ASD

GO:0007176 regulation of epidermal growth factor receptor activity (20)

GeneInput weightStandardRank
FBXW7--198
ADORA1--960
ADRA2A0.2511399
APP--1515
TGFA--1873
NCK2--3077
ADAM17--5323
ERRFI1--6649
ZFYVE28--7781
ADRA2C--8551
EREG--9052
SHC1--10045
ADRA2B--10119
EPGN--12503
EGF0.25112881
PSEN1--18523
ZGPAT--20366
CBLC--21497
SNX6--22713
PSEN2--23095

Network

GO:0007176

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
APPamyloid beta (A4) precursor protein Entrez:351  HGNC: 620  Ensembl: ENSG00000142192  HPRD: 00100 
TGFAtransforming growth factor, alpha Entrez:7039  HPRD: 07522  HGNC: 11765  Ensembl: ENSG00000163235 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADORA1adenosine A1 receptor
ADRA2Aadrenoceptor alpha 2A
APPamyloid beta (A4) precursor protein
TGFAtransforming growth factor, alpha
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADORA1ADORA1adenosine A1 receptor
ADRA2AADRA2Aadrenoceptor alpha 2A
APPAPPamyloid beta (A4) precursor protein
TGFATGFAtransforming growth factor, alpha

Troyanskaya Laboratory - Princeton University