ASD

GO:0046068 cGMP metabolic process (21)

GeneInput weightStandardRank
ATP2B20.511
HTR2C0.25146
GUCY1B3--560
PDE2A--1591
GUCY1A2--1629
GUCY1A3--1730
PDE1B--1791
PDE11A--2107
GUCY2F--3945
GUCY2D--15204
HTR2B--5233
NPPB--5967
NPR2--16150
RORA--6355
NPPC--7442
GUCY2C--8098
PDE5A--8315
GUCA2B--8899
NPPA--110598
AQP1--21019
NPR1--24360

Network

GO:0046068

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
GUCY1B3guanylate cyclase 1, soluble, beta 3 Entrez:2983  HGNC: 4687  Ensembl: ENSG00000061918  HPRD: 00769 
PDE2Aphosphodiesterase 2A, cGMP-stimulated Entrez:5138  HGNC: 8777  Ensembl: ENSG00000186642  HPRD: 04041 
GUCY1A2guanylate cyclase 1, soluble, alpha 2 Entrez:2977  Ensembl: ENSG00000152402  HGNC: 4684  HPRD: 03146 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GUCY1B3guanylate cyclase 1, soluble, beta 3
PDE2Aphosphodiesterase 2A, cGMP-stimulated
GUCY1A2guanylate cyclase 1, soluble, alpha 2
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GUCY1B3GUCY1B3guanylate cyclase 1, soluble, beta 3
PDE2APDE2Aphosphodiesterase 2A, cGMP-stimulated
GUCY1A2GUCY1A2guanylate cyclase 1, soluble, alpha 2

Troyanskaya Laboratory - Princeton University