ASD

GO:0010863 positive regulation of phospholipase C activity (106)

GeneInput weightStandardRank
GNB1--15
HTR2A0.25151
ADCY2--102
PRKCE--156
CALM3--195
GRM50.251196
CRHR1--280
CALCA--460
ADCY10.251466
DRD50.251482
GNAQ--490
NTSR2--493
CCKBR--533
PRKACB--544
PRKCA--613
DRD10.251662
CAMK4--673
CALM1--708
ITPR1--1802
PTGER3--842
ADRA1A--937
CREB1--991
HCRTR20.2511101
DLC1--1105
ADCYAP1R1--1132
PRKAR1B--1163
PDE1C--1202
PRKCG--11280
EDNRB--11322
NMBR--1448
PRKAR2B--1512
ADRA2A0.2511556
PDE1A--1704
GNG13--1713
PRKAR1A--11718
PDE1B--1791
ADCY8--1906
DRD20.2512071
CHRM2--2223
CALM2--2360
LHCGR0.2512362
ADCY9--2435
EGFR--12811
AGTR1--12898
S1PR1--2910
LPAR1--2975
AVPR1A0.513141
GNA11--3167
EDNRA--13271
PRKACG--3335
GNA14--3434
NGF0.2513749
AGT--13783
NPR3--3798
ADCY5--4352
ADCY6--4362
ARHGAP6--4472
P2RY1--4483
AVPR1B0.2514502
ADCY3--4618
ADRBK1--4864
NTRK10.2514883
RXFP3--5237
P2RY4--5261
HRH1--5298
PRKCD--5824
NMUR2--5836
PLCG1--5952
HOMER10.2516115
MC3R0.2516322
CHRM1--6680
GPR55--7357
RASGRP4--7359
HCRT0.2517434
F2RL3--7474
CCKAR--7616
TACR1--7688
PLCE1--7692
ADCY4--8354
ITPR2--8681
PRKACA--8797
EDN1--9566
FGF2--9627
LPAR3--10488
MS4A2--10551
SELE--10573
CXCR2--11514
GPR139--11802
F2R--12498
FRS2--12610
NMUR1--13186
TGM2--13660
LPAR2--14606
C5AR1--16349
P2RY11--18359
GNA15--20239
PRKAR2A--21408
LTB4R--21535
SLC9A3R1--21807
P2RY6--21915
ITPR3--22312
PLCB2--22340
S1PR4--22365
P2RY2--24073
ANG--124265
ADCY7--25198

Network

GO:0010863

Network
Enrichment
NameDescriptionExternal IDs
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ADCY2adenylate cyclase 2 (brain)
PRKCEprotein kinase C, epsilon
CALM3calmodulin 3 (phosphorylase kinase, delta)
Query geneGeneGene descriptionEdge score
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ADCY2ADCY2adenylate cyclase 2 (brain)
PRKCEPRKCEprotein kinase C, epsilon
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)

Troyanskaya Laboratory - Princeton University