ASD

GO:0070936 protein K48-linked ubiquitination (32)

GeneInput weightStandardRank
UBE2E3--574
UBE2D2--600
TTC3--627
PARK20.251634
UBE2D3--661
UBE3A0.251917
RNF4--1036
UBE2A0.2511473
CDC34--1858
UBE2G1--2263
UBE2B--2708
UBE2K--2746
UBE2R2--2944
TNFAIP3--3628
RNF152--3891
RNF6--14587
MARCH6--4985
RNF5--5935
UBE2E1--6513
UBE2G2--6750
ARIH2--7215
UBE2Q2--8469
ITCH--10863
UBE2E2--15070
UBE2H0.25115142
RNF187--15734
RNF146--20728
RNF216--23131
UBE2D1--23789
UBE2D4--23886
UBE2T--24873
UBE2C--25279

Network

GO:0070936

Network
Enrichment
NameDescriptionExternal IDs
UBE2E3ubiquitin-conjugating enzyme E2E 3 Entrez:10477  HGNC: 12479  Ensembl: ENSG00000170035  HPRD: 05000 
UBE2D2ubiquitin-conjugating enzyme E2D 2 Entrez:7322  HPRD: 04268  HGNC: 12475  Ensembl: ENSG00000131508 
TTC3tetratricopeptide repeat domain 3 Entrez:7267  HPRD: 03773  HGNC: 12393  Ensembl: ENSG00000182670 
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HPRD: 03967  HGNC: 8607  Ensembl: ENSG00000185345 
UBE2D3ubiquitin-conjugating enzyme E2D 3 Entrez:7323  Ensembl: ENSG00000109332  HPRD: 04269  HGNC: 12476 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBE2E3ubiquitin-conjugating enzyme E2E 3
UBE2D2ubiquitin-conjugating enzyme E2D 2
TTC3tetratricopeptide repeat domain 3
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
UBE2D3ubiquitin-conjugating enzyme E2D 3
Query geneGeneGene descriptionEdge score
UBE2E3UBE2E3ubiquitin-conjugating enzyme E2E 3
UBE2D2UBE2D2ubiquitin-conjugating enzyme E2D 2
TTC3TTC3tetratricopeptide repeat domain 3
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
UBE2D3UBE2D3ubiquitin-conjugating enzyme E2D 3

Troyanskaya Laboratory - Princeton University