ASD

GO:0045687 positive regulation of glial cell differentiation (21)

GeneInput weightStandardRank
OLIG2--420
NKX2-2--771
DICER1--1834
RELA--1352
HDAC2--1413
ID2--1719
RTN4--1776
NTF30.2512294
SERPINE2--2896
NKX6-1--3174
NOTCH1--13360
ZNF488--3692
CXCR4--4014
ASPA--14515
NKX6-2--5422
SHH--115942
TP73--15964
LIF--20888
PRPF19--21797
PPARG--121945
CLCF1--22182

Network

GO:0045687

Network
Enrichment
NameDescriptionExternal IDs
OLIG2oligodendrocyte lineage transcription factor 2 Entrez:10215  HPRD: 07334  Ensembl: ENSG00000205927  HGNC: 9398 
NKX2-2NK2 homeobox 2 Entrez:4821  Ensembl: ENSG00000125820  HGNC: 7835  HPRD: 05213 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
RELAv-rel avian reticuloendotheliosis viral oncogene homolog A Entrez:5970  HGNC: 9955  HPRD: 01241  Ensembl: ENSG00000173039 
HDAC2histone deacetylase 2 Entrez:3066  Ensembl: ENSG00000196591  HGNC: 4853  HPRD: 05521 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
OLIG2oligodendrocyte lineage transcription factor 2
NKX2-2NK2 homeobox 2
DICER1dicer 1, ribonuclease type III
RELAv-rel avian reticuloendotheliosis viral oncogene homolog A
HDAC2histone deacetylase 2
Query geneGeneGene descriptionEdge score
OLIG2OLIG2oligodendrocyte lineage transcription factor 2
NKX2-2NKX2-2NK2 homeobox 2
DICER1DICER1dicer 1, ribonuclease type III
RELARELAv-rel avian reticuloendotheliosis viral oncogene homolog A
HDAC2HDAC2histone deacetylase 2

Troyanskaya Laboratory - Princeton University