ASD

GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway (7)

GeneInput weightStandardRank
DRD50.251482
DRD10.251662
GNAL--860
GNAS--12352
DRD30.2512757
ADCY5--4352
SLC9A3R1--21807

Network

GO:0007191

Network
Enrichment
NameDescriptionExternal IDs
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Entrez:2774  HGNC: 4388  Ensembl: ENSG00000141404  HPRD: 00758 
GNASGNAS complex locus Entrez:2778  HGNC: 4392  HPRD: 00761  Ensembl: ENSG00000087460 
DRD3dopamine receptor D3 Entrez:1814  HGNC: 3024  Ensembl: ENSG00000151577  HPRD: 00540 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DRD5dopamine receptor D5
DRD1dopamine receptor D1
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNASGNAS complex locus
DRD3dopamine receptor D3
Query geneGeneGene descriptionEdge score
DRD5DRD5dopamine receptor D5
DRD1DRD1dopamine receptor D1
GNALGNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNASGNASGNAS complex locus
DRD3DRD3dopamine receptor D3

Troyanskaya Laboratory - Princeton University