ASD

GO:0030514 negative regulation of BMP signaling pathway (26)

GeneInput weightStandardRank
SFRP1--204
TRIM33--1692
CHRD--697
SMAD7--1283
SMAD6--2079
HIPK2--2306
LEMD3--12358
SOSTDC1--2578
GREM1--2654
WNT5A--2870
BMPER--3267
NOTCH1--13360
SFRP2--3758
SKI--4231
SMURF1--4696
CER1--5192
SOST--5795
FBN1--16138
DKK1--6892
NOG--17650
VWC2--10359
SKOR1--16408
FZD1--22086
FSTL3--24700
CAV1--124767
TWSG1--25171

Network

GO:0030514

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
TRIM33tripartite motif containing 33 Entrez:51592  HPRD: 10423  HGNC: 16290  Ensembl: ENSG00000197323 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
SMAD6SMAD family member 6 Entrez:4091  Ensembl: ENSG00000137834  HPRD: 04240  HGNC: 6772 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
TRIM33tripartite motif containing 33
CHRDchordin
SMAD7SMAD family member 7
SMAD6SMAD family member 6
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
TRIM33TRIM33tripartite motif containing 33
CHRDCHRDchordin
SMAD7SMAD7SMAD family member 7
SMAD6SMAD6SMAD family member 6

Troyanskaya Laboratory - Princeton University