ASD

GO:0010656 negative regulation of muscle cell apoptosis (11)

GeneInput weightStandardRank
NRG10.251285
LRP6--778
BMP7--987
IGF10.2511993
ILK--2917
HAND2--3736
SFRP2--3758
GHRH--4568
NKX2-50.2515490
EDN1--9566
APOH--11155

Network

GO:0010656

Network
Enrichment
NameDescriptionExternal IDs
NRG1neuregulin 1 Entrez:3084  HPRD: 00802  Ensembl: ENSG00000157168  HGNC: 7997 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
IGF1insulin-like growth factor 1 (somatomedin C) Entrez:3479  HPRD: 00936  Ensembl: ENSG00000017427  HGNC: 5464 
ILKintegrin-linked kinase Entrez:3611  HPRD: 03842  Ensembl: ENSG00000166333  HGNC: 6040 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NRG1neuregulin 1
LRP6low density lipoprotein receptor-related protein 6
BMP7bone morphogenetic protein 7
IGF1insulin-like growth factor 1 (somatomedin C)
ILKintegrin-linked kinase
Query geneGeneGene descriptionEdge score
NRG1NRG1neuregulin 1
LRP6LRP6low density lipoprotein receptor-related protein 6
BMP7BMP7bone morphogenetic protein 7
IGF1IGF1insulin-like growth factor 1 (somatomedin C)
ILKILKintegrin-linked kinase

Troyanskaya Laboratory - Princeton University