ASD

GO:0032909 regulation of transforming growth factor-beta2 production (7)

GeneInput weightStandardRank
TGFB2--625
HIF1A--1008
ATF2--1137
SMAD3--1541
SMAD4--2927
WNT11--4528
GATA6--113349

Network

GO:0032909

Network
Enrichment
NameDescriptionExternal IDs
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
ATF2activating transcription factor 2 Entrez:1386  Ensembl: ENSG00000115966  HPRD: 00443  HGNC: 784 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TGFB2transforming growth factor, beta 2
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ATF2activating transcription factor 2
SMAD3SMAD family member 3
SMAD4SMAD family member 4
Query geneGeneGene descriptionEdge score
TGFB2TGFB2transforming growth factor, beta 2
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ATF2ATF2activating transcription factor 2
SMAD3SMAD3SMAD family member 3
SMAD4SMAD4SMAD family member 4

Troyanskaya Laboratory - Princeton University