ASD

GO:0003279 cardiac septum development (31)

GeneInput weightStandardRank
SOX11--66
FGFR2--1165
SALL1--408
SOX4--581
PROX1--962
ZFPM2--11023
SMAD7--1283
TBX5--1743
WHSC1--2663
HAND1--2763
WNT5A--2870
GATA3--3207
HOXA13--3602
DVL3--4438
WNT11--4528
BMP4--15180
NKX2-50.2515490
HES10.2515662
TBX20--16000
STRA6--17612
SALL4--9465
RBM15--10015
CRELD1--10776
GATA4--111137
FRS2--12610
IFT88--12821
GATA6--113349
FGFRL1--13718
FZD2--13981
CYR61--19764
FZD1--22086

Network

GO:0003279

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
PROX1prospero homeobox 1 Entrez:5629  HPRD: 03330  HGNC: 9459  Ensembl: ENSG00000117707 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
FGFR2fibroblast growth factor receptor 2
SALL1sal-like 1 (Drosophila)
SOX4SRY (sex determining region Y)-box 4
PROX1prospero homeobox 1
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
FGFR2FGFR2fibroblast growth factor receptor 2
SALL1SALL1sal-like 1 (Drosophila)
SOX4SOX4SRY (sex determining region Y)-box 4
PROX1PROX1prospero homeobox 1

Troyanskaya Laboratory - Princeton University