ASD

GO:0010717 regulation of epithelial to mesenchymal transition (30)

GeneInput weightStandardRank
PPP2CA--21
SFRP1--204
TGFB2--625
SMAD7--1283
SMAD3--1541
LEF1--1731
TBX5--1743
NKX2-1--2488
GREM1--2654
SMAD4--2927
EPB41L5--3311
NOTCH1--13360
DAB2IP--3635
SFRP2--3758
TGFB3--15321
BCL9L--5421
TCF7L2--15670
AXIN2--15927
TWIST1--16128
CTNNB10.2516229
ZNF703--6470
SMAD2--7224
BAMBI--7548
SNAI1--8474
TGFBR3--8717
TGFB10.25114736
EFNA1--21813
TGFB1I1--22730
WWTR1--22777
COL1A1--124560

Network

GO:0010717

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SFRP1secreted frizzled-related protein 1
TGFB2transforming growth factor, beta 2
SMAD7SMAD family member 7
SMAD3SMAD family member 3
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SFRP1SFRP1secreted frizzled-related protein 1
TGFB2TGFB2transforming growth factor, beta 2
SMAD7SMAD7SMAD family member 7
SMAD3SMAD3SMAD family member 3

Troyanskaya Laboratory - Princeton University