ASD

GO:0014032 neural crest cell development (43)

GeneInput weightStandardRank
SOX11--66
NRG10.251285
RET--1384
HIF1A--1008
SOX9--11045
EDNRB--11322
NRP20.2511360
ISL1--1441
EDN3--11522
CYP26A1--2181
FOXD3--2272
KITLG--3019
EDNRA--13271
ALDH1A2--3466
GBX2--3588
HAND2--3736
GDNF--14462
ZEB2--4607
SOX8--4770
HTR2B--5233
FOXD1--5256
FOXD2--5493
HES10.2515662
SMO0.2515864
EFNB1--16175
SEMA3C--6197
CYP26C1--6885
FOXD4L1--7290
FOXC2--8308
EDN1--9566
RDH10--9600
FOXD4--9835
FGF19--10321
FOXD4L4--10472
ACVR1--111780
NRTN--13324
SHH--115942
FOXD4L5--16935
FOXD4L2--17995
LAMA5--19186
FOXD4L6--19463
FOXC1--122868
SNAI2--122934

Network

GO:0014032

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
NRG1neuregulin 1 Entrez:3084  HPRD: 00802  Ensembl: ENSG00000157168  HGNC: 7997 
RETret proto-oncogene Entrez:5979  HGNC: 9967  Ensembl: ENSG00000165731  HPRD: 01266 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
SOX9SRY (sex determining region Y)-box 9 Entrez:6662  HPRD: 06427  HGNC: 11204  Ensembl: ENSG00000125398 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
NRG1neuregulin 1
RETret proto-oncogene
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
SOX9SRY (sex determining region Y)-box 9
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
NRG1NRG1neuregulin 1
RETRETret proto-oncogene
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
SOX9SOX9SRY (sex determining region Y)-box 9

Troyanskaya Laboratory - Princeton University