ASD

GO:0019882 antigen processing and presentation (126)

GeneInput weightStandardRank
PSMA1--42
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
PSMA5--219
BCAP31--267
PSMB1--318
PSMA3--373
PSMC4--380
PSMC6--405
PSMB7--554
PSMB4--562
PSMD2--595
PSMB6--696
PSMA7--782
PSMC3--794
PSMC5--831
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
PSMD11--943
PSMC2--952
PSMD13--994
PSMD4--1166
HLA-E--1169
HLA-G--1292
UBE2A0.2511473
HLA-F--1479
PSMA6--1492
PSME4--1576
PSMA2--1693
HLA-B0.2511695
NPEPPS--1838
HLA-C--1932
PSMD10--2012
PSMD12--2120
TAPBP--12308
PSMD7--2386
ULBP1--2393
TAP1--12912
CD1A--3105
HLA-A0.2513215
CLEC4M--3417
SEC24C--4508
CD1B--4631
IFNG--15255
UBC--5781
AP3D1--5872
SEC24B--6372
HLA-DPB2--6393
B2M--7118
MARCH1--7173
CD1E--7321
PSME2--7488
PSMB9--7654
PSMB2--7801
CTSE--7967
PSMA8--8114
HLA-DRB5--8906
CD209--9761
RAET1E--10221
PSME1--11612
SEC23A--11647
HLA-DOA--11824
HLA-DQB1--111826
ULBP3--12280
PSMB8--12378
TPP2--12568
HLA-DQB2--12619
CD8A--13130
BLMH--13327
HLA-H--13532
CD1C--13580
PSMD9--13761
HLA-DRB3--14053
ICAM1--14063
CD1D--14177
PSMB11--14440
PSMB10--14502
HLA-DPB1--14599
HLA-DRB4--15120
IFI30--15194
HLA-DQA1--115297
HLA-DRA--15730
PSME3--17451
FCER1G--17885
PSMD5--18391
AZGP1--18745
SLC11A1--19965
MICA--20384
HLA-DQA2--20427
FCGRT--20899
HFE0.25120917
HLA-DPA1--21088
PDIA3--21181
ERAP2--21370
RAET1G--21520
SEC24A--21594
RAET1L--21680
ULBP2--21754
UBB--22223
CALR--22356
PROCR--22491
CD74--22633
HLA-DOB--22678
SEC24D--22780
RPS27A--22920
PSMF1--22952
HLA-DRB10.25123030
HLA-DMA--23189
SEC13--23220
HLA-DMB--23259
MARCH8--23556
MICB--23591
LNPEP--23644
TAPBPL--23860
ERAP1--24025
UBA52--24116
PSMB5--24489
CANX--24885
TAP2--125206
SEC31A--25408
SAR1B--25587
MR1--25687

Network

GO:0019882

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Entrez:5714  Ensembl: ENSG00000099341  HPRD: 10171  HGNC: 9566 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Troyanskaya Laboratory - Princeton University