ASD

GO:0021522 spinal cord motor neuron differentiation (17)

GeneInput weightStandardRank
CACNA1A--1231
PAX60.251355
SOX4--581
NKX2-2--771
ISL1--1441
MDGA20.2512830
HOXD10--2845
NKX6-1--3174
HOXC10--4404
PHOX2A--4551
GIGYF2--14627
NKX6-2--5422
MNX1--5932
LHX4--8278
GLI3--19032
CLN8--121998
ABT1--22292

Network

GO:0021522

Network
Enrichment
NameDescriptionExternal IDs
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
NKX2-2NK2 homeobox 2 Entrez:4821  Ensembl: ENSG00000125820  HGNC: 7835  HPRD: 05213 
ISL1ISL LIM homeobox 1 Entrez:3670  HGNC: 6132  Ensembl: ENSG00000016082  HPRD: 02650 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
PAX6paired box 6
SOX4SRY (sex determining region Y)-box 4
NKX2-2NK2 homeobox 2
ISL1ISL LIM homeobox 1
Query geneGeneGene descriptionEdge score
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
PAX6PAX6paired box 6
SOX4SOX4SRY (sex determining region Y)-box 4
NKX2-2NKX2-2NK2 homeobox 2
ISL1ISL1ISL LIM homeobox 1

Troyanskaya Laboratory - Princeton University