ASD

GO:0000077 DNA damage checkpoint (119)

GeneInput weightStandardRank
PSMA1--42
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
PSMA5--219
PSMB1--318
PSMA3--373
PSMC4--380
PSMC6--405
PSMB7--554
PSMB4--562
SOX4--581
PSMD2--595
PPP2R5C--681
PSMB6--696
DGKZ--725
PSMA7--782
PSMC3--794
PSMC5--831
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
PSMD11--943
PSMC2--952
PSMD13--994
CDKN1B--1067
PSMD4--1166
PSMA6--1492
PSME4--1576
PSMA2--1693
CLOCK0.2511833
PSMD10--2012
FOXN3--2066
PSMD12--2120
MSH2--12299
PSMD7--2386
TAOK20.2512490
CDC14B--2703
NEK11--2723
GML--2793
H2AFX--3754
FZR1--3987
TAOK3--4471
CDKN1A--4620
MAPK14--4729
BRSK1--4979
CCND1--15288
TAOK1--5452
MDM2--5588
UBC--5781
BABAM1--6310
PCBP4--6619
PSME2--7488
PSMB9--7654
PSMB2--7801
PSMA8--8114
RPA4--9999
TIPRL--10063
FOXO4--10242
ATM--110590
MDC1--11232
PSME1--11612
RFWD2--12054
UIMC1--12322
PSMB8--12378
RBM38--12396
PSMD9--13761
PSMB11--14440
PSMB10--14502
PLK5--14706
RAD9A--15302
TP73--15964
PSME3--17451
PSMD5--18391
USP28--21173
HINFP--21497
HUS1--21730
NBN--121778
TP530.25121968
FBXO31--22074
UBB--22223
BRE--22289
CCNG1--22384
CLSPN--22424
ATRIP--22786
CEP63--22823
RPS27A--22920
PSMF1--22952
XPC--123003
TRIAP1--23071
FBXO6--23116
BRCC3--23262
BRIP1--123410
RAD1--23948
FAM175A--23969
CDK1--24001
CDK2--24011
INTS7--24075
CHEK2--124100
TP63--124113
UBA52--24116
BRCA1--124158
RFWD3--24220
RHNO1--24255
PSMB5--24489
RAD17--24604
GTSE1--24676
RPS27L--24874
RINT1--25002
ATR--125123
DTL--25201
PML--25248
CCNA2--25594
TIPIN--25623
PLK1--25689
BLM--125773
CHEK1--25817

Network

GO:0000077

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Entrez:5714  Ensembl: ENSG00000099341  HPRD: 10171  HGNC: 9566 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Troyanskaya Laboratory - Princeton University