ASD

GO:0014033 neural crest cell differentiation (49)

GeneInput weightStandardRank
SOX11--66
SFRP1--204
NRG10.251285
RET--1384
LRP6--778
HIF1A--1008
SOX9--11045
EDNRB--11322
NRP20.2511360
ISL1--1441
EDN3--11522
CYP26A1--2181
FOXD3--2272
KITLG--3019
EDNRA--13271
ALDH1A2--3466
GBX2--3588
HAND2--3736
GDNF--14462
ZEB2--4607
SOX8--4770
HTR2B--5233
FOXD1--5256
FOXD2--5493
HES10.2515662
SMO0.2515864
EFNB1--16175
SEMA3C--6197
CYP26C1--6885
WNT8A--7061
FOXD4L1--7290
FOXC2--8308
WNT10A--9302
FRZB--9553
EDN1--9566
RDH10--9600
FOXD4--9835
FGF19--10321
FOXD4L4--10472
ACVR1--111780
NRTN--13324
FOXS1--15328
SHH--115942
FOXD4L5--16935
FOXD4L2--17995
LAMA5--19186
FOXD4L6--19463
FOXC1--122868
SNAI2--122934

Network

GO:0014033

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
NRG1neuregulin 1 Entrez:3084  HPRD: 00802  Ensembl: ENSG00000157168  HGNC: 7997 
RETret proto-oncogene Entrez:5979  HGNC: 9967  Ensembl: ENSG00000165731  HPRD: 01266 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
SFRP1secreted frizzled-related protein 1
NRG1neuregulin 1
RETret proto-oncogene
LRP6low density lipoprotein receptor-related protein 6
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
SFRP1SFRP1secreted frizzled-related protein 1
NRG1NRG1neuregulin 1
RETRETret proto-oncogene
LRP6LRP6low density lipoprotein receptor-related protein 6

Troyanskaya Laboratory - Princeton University