ASD

GO:0060402 calcium ion transport into cytosol (29)

GeneInput weightStandardRank
HTR2C0.25146
HTR2A0.25151
PRKCE--156
SLC8A2--232
JPH3--503
CACNA1C--1558
RYR2--1862
ADRA1A--937
SLC8A1--1339
FKBP1B--1700
DRD20.2512071
JPH4--2676
JPH1--2836
SLC8A3--3637
HTR2B--5233
XCR1--5374
XCL1--6562
GLP1R--7291
FGF2--9627
CCL19--11890
JPH2--13414
RYR1--114071
BBC3--14408
PTPRC--15053
CCL21--19130
CCR7--21314
ITPR3--22312
IBTK--23069
LCK--24966

Network

GO:0060402

Network
Enrichment
NameDescriptionExternal IDs
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 2 Entrez:6543  Ensembl: ENSG00000118160  HGNC: 11069  HPRD: 15990 
JPH3junctophilin 3 Entrez:57338  Ensembl: ENSG00000154118  HGNC: 14203  HPRD: 05589 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
PRKCEprotein kinase C, epsilon
SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 2
JPH3junctophilin 3
Query geneGeneGene descriptionEdge score
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
PRKCEPRKCEprotein kinase C, epsilon
SLC8A2SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 2
JPH3JPH3junctophilin 3

Troyanskaya Laboratory - Princeton University