ASD

GO:0048169 regulation of long-term neuronal synaptic plasticity (24)

GeneInput weightStandardRank
CAMK2B0.25111
GRIN2A0.25156
GRIK20.51142
KRAS--1143
GRIN1--167
GRM50.251196
NF10.251333
SNCA--1401
DRD50.251482
KCNJ10--1518
GRIN2B1.01599
RIMS1--622
DRD10.251662
DLG4--707
RAB11A--1974
DRD20.2512071
NETO1--2314
SYP--2394
SYNGR1--3055
NPTN--3227
EGR1--3527
AGT--13783
NRAS--15506
HRAS0.25112845

Network

GO:0048169

Network
Enrichment
NameDescriptionExternal IDs
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIK2glutamate receptor, ionotropic, kainate 2
KRASKirsten rat sarcoma viral oncogene homolog
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
Query geneGeneGene descriptionEdge score
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
KRASKRASKirsten rat sarcoma viral oncogene homolog
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1

Troyanskaya Laboratory - Princeton University