ASD

GO:0017158 regulation of calcium ion-dependent exocytosis (22)

GeneInput weightStandardRank
SYT1--5
PLCB1--161
CADPS--119
CACNA1A--1231
ADRA2A0.2511556
SYT7--1604
DOC2A0.2511649
SCAMP50.2511910
GLRA1--2146
CDK50.2513113
NOTCH1--13360
CACNA1H1.013918
SYT9--5308
TRPV6--7049
RPH3AL--7341
DOC2B--9220
FGF2--9627
STXBP3--10747
ZP4--12785
REST--13067
ZP3--15811
B4GALT1--121783

Network

GO:0017158

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
ADRA2Aadrenoceptor alpha 2A
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
ADRA2AADRA2Aadrenoceptor alpha 2A

Troyanskaya Laboratory - Princeton University