ASD

GO:0051969 regulation of transmission of nerve impulse (176)

GeneInput weightStandardRank
ATP2B20.511
CNR10.25110
CAMK2B0.25111
CTNND2--16
NTRK20.25128
HTR2A0.25151
GRIN2A0.25156
ERBB40.25164
NEUROD2--68
ADNP0.5191
CDH2--130
GRIK20.51142
KRAS--1143
PRKCE--156
GRIN1--167
CAMK2A--183
GRM50.251196
RASGRF1--213
GRIK1--216
CACNA1A--1231
SLC6A10.251238
MEF2C0.251248
NLGN10.251265
MAPK8IP2--275
PPP3CA--278
CRHR1--280
MAP1B--300
DBN1--332
NF10.251333
CALB10.251342
GABBR10.251352
GRM3--399
SNCA--1401
PFN2--431
CNTN2--438
STX1A0.251449
DRD50.251482
ADORA1--498
NPY5R0.251512
KCNJ10--1518
RAB3A0.251520
GRM10.251523
CCKBR--533
TAC10.251543
GRIN2B1.01599
RIMS1--622
PARK20.251634
RAPGEF40.251635
LGI1--646
BHLHE40--657
STXBP1--659
DRD10.251662
NR2E10.251699
DLG4--707
NCDN--744
BDNF0.251754
DICER1--1834
SNCAIP--855
NOS10.251908
CHRNA3--910
USP46--926
ADRA1A--937
CPLX20.251956
GRIK30.251976
YWHAH--1109
GRM80.2511152
GRIA4--1176
CARTPT0.2511181
BCAN--1186
VGF0.2511243
ACHE--1266
GNAI3--1340
UNC13A--1521
EDN3--11522
KCNC3--11537
GNAI1--1613
KCNMB4--1626
CHRNA70.511657
SLC24A2--1691
YWHAG--1799
PPFIA3--1813
GFAP--11886
RAB11A--1974
CNTN41.012038
DRD20.2512071
BCHE--2123
GLRA1--2146
KCNC4--2276
MYRF--2286
NTF30.2512294
NETO1--2314
SYP--2394
SLC18A1--2477
DRD30.2512757
TNR--2784
SERPINE2--2896
SPECC1L--3048
SYNGR1--3055
CDK50.2513113
AVPR1A0.513141
S100B--3142
PTGS20.2513176
NPTN--3227
SLC6A40.2513328
SNCG--3377
EGR1--3527
CHRNB4--3723
NGF0.2513749
NISCH--3766
AGT--13783
CPLX3--3906
GIP--3965
HES5--4001
EGR20.2514059
GDNF--14462
OXTR0.514494
IL6--14578
PXK--4731
ADIPOQ0.2514834
SLC1A30.2515029
IFNG--15255
NRAS--15506
HTR1B0.2515751
MEF2A--6060
NLGN2--6159
CTNNB10.2516229
GNAI2--6384
DRD40.2517058
HCRT0.2517434
ABHD6--7605
ARRB2--7639
TACR1--7688
KISS1R--8159
CNR20.2518581
CHAT--8747
PRKACA--8797
ANAPC2--8902
PINK1--18983
UCN--8987
MYLK2--19540
EDN1--9566
ADORA2A0.2519605
ARC0.2519982
OXT0.25110022
MGLL--10038
CPLX4--10836
PEBP1--11226
PMCH--11242
RGS14--11308
NAPB--11425
AVP--111615
P2RX3--11797
TG--12189
UNC13B--12427
HRAS0.25112845
PLAT--13559
SLC30A1--14226
GIPC1--15140
PATE4--16329
OPHN10.5116404
NMU--16499
CD380.25117453
TNF0.25119823
SHISA9--20085
PSEN1--20241
CHRNB20.25120277
EIF2AK3--20407
KCNQ4--120957
CHRFAM7A--21295
APOE0.25121310
PSEN2--21431
KLK8--22103
GRID2IP--22273
MMP9--23766
RNF10--23821
CDC20--24914

Network

GO:0051969

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
CTNND2catenin (cadherin-associated protein), delta 2 Entrez:1501  HGNC: 2516  HPRD: 09181  Ensembl: ENSG00000169862 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
CNR1cannabinoid receptor 1 (brain)
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
CTNND2catenin (cadherin-associated protein), delta 2
NTRK2neurotrophic tyrosine kinase, receptor, type 2
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
CNR1CNR1cannabinoid receptor 1 (brain)
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta
CTNND2CTNND2catenin (cadherin-associated protein), delta 2
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2

Troyanskaya Laboratory - Princeton University