ASD

GO:0030801 positive regulation of cyclic nucleotide metabolic process (36)

GeneInput weightStandardRank
ADNP0.5191
DRD50.251482
DRD10.251662
ADRB1--866
ADCYAP1R1--1132
PTHLH--11269
AKAP5--1517
GUCY1A3--1730
MC2R--1919
GHRHR--2312
GSK3A--2346
ABCA1--12698
WNT5A--2870
SPECC1L--3048
AKAP12--3150
MC4R0.2513280
MC5R--3358
GCG--4286
GHRH--4568
MRAP2--4941
PTH--5481
MC3R0.2516322
RXFP2--16360
NPPC--7442
MC1R--18333
GIPR--9148
ADORA2A0.2519605
MRAP--10738
ADORA2B--11164
INSL3--111614
AVP--111615
FZD2--13981
GPR65--20238
APOE0.25121310
NPR1--24360
ADCY7--25198

Network

GO:0030801

Network
Enrichment
NameDescriptionExternal IDs
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I Entrez:117  HGNC: 242  Ensembl: ENSG00000078549  HPRD: 00045 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADNPactivity-dependent neuroprotector homeobox
DRD5dopamine receptor D5
DRD1dopamine receptor D1
ADRB1adrenoceptor beta 1
ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
Query geneGeneGene descriptionEdge score
ADNPADNPactivity-dependent neuroprotector homeobox
DRD5DRD5dopamine receptor D5
DRD1DRD1dopamine receptor D1
ADRB1ADRB1adrenoceptor beta 1
ADCYAP1R1ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

Troyanskaya Laboratory - Princeton University