ASD

GO:0034199 activation of protein kinase A activity (16)

GeneInput weightStandardRank
ADCY2--102
ADCY10.251466
PRKACB--544
PRKAR1B--1163
PRKAR2B--1512
PRKAR1A--11718
ADCY8--1906
ADCY9--2435
PRKACG--3335
ADCY5--4352
ADCY6--4362
ADCY3--4618
ADCY4--8354
PRKACA--8797
PRKAR2A--21408
ADCY7--25198

Network

GO:0034199

Network
Enrichment
NameDescriptionExternal IDs
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
ADCY1adenylate cyclase 1 (brain) Entrez:107  HGNC: 232  HPRD: 00053  Ensembl: ENSG00000164742 
PRKACBprotein kinase, cAMP-dependent, catalytic, beta Entrez:5567  HPRD: 01482  HGNC: 9381  Ensembl: ENSG00000142875 
PRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta Entrez:5575  HPRD: 01485  Ensembl: ENSG00000188191  HGNC: 9390 
PRKAR2Bprotein kinase, cAMP-dependent, regulatory, type II, beta Entrez:5577  Ensembl: ENSG00000005249  HGNC: 9392  HPRD: 01486 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADCY2adenylate cyclase 2 (brain)
ADCY1adenylate cyclase 1 (brain)
PRKACBprotein kinase, cAMP-dependent, catalytic, beta
PRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2Bprotein kinase, cAMP-dependent, regulatory, type II, beta
Query geneGeneGene descriptionEdge score
ADCY2ADCY2adenylate cyclase 2 (brain)
ADCY1ADCY1adenylate cyclase 1 (brain)
PRKACBPRKACBprotein kinase, cAMP-dependent, catalytic, beta
PRKAR1BPRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2BPRKAR2Bprotein kinase, cAMP-dependent, regulatory, type II, beta

Troyanskaya Laboratory - Princeton University