ASD

GO:0051149 positive regulation of muscle cell differentiation (44)

GeneInput weightStandardRank
PLCB1--161
CDH2--130
MEG3--201
MEF2C0.251248
NRG10.251285
CTNNA2--654
ADRB1--866
PIK3R10.2511065
CDC42--1083
MAPK11--1258
BTG1--1268
SPAG9--1398
SHOX2--2149
MYOD1--2280
ABL1--2653
MYF6--2717
NEO1--2831
ILK--2917
CDON--3482
HOPX--4054
TSHZ3--4327
MAPK14--4729
BMP4--15180
MYOCD--5769
TCF3--5880
MEF2A--6060
MYF5--6153
CTNNB10.2516229
BOC--6380
NEU2--6474
BNIP2--6921
RBM4--8366
MYOG--8556
MAP2K6--10398
ZFHX3--110438
MESP1--10948
CAMK1--11696
CTNNA1--11705
IGFBP3--13922
TGFB10.25114736
SHH--115942
MAPK12--19748
NTN3--20955
CDH15--21064

Network

GO:0051149

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CDH2cadherin 2, type 1, N-cadherin (neuronal) Entrez:1000  Ensembl: ENSG00000170558  HGNC: 1759  HPRD: 00226 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
MEF2Cmyocyte enhancer factor 2C Entrez:4208  HGNC: 6996  Ensembl: ENSG00000081189  HPRD: 02809 
NRG1neuregulin 1 Entrez:3084  HPRD: 00802  Ensembl: ENSG00000157168  HGNC: 7997 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CDH2cadherin 2, type 1, N-cadherin (neuronal)
MEG3maternally expressed 3 (non-protein coding)
MEF2Cmyocyte enhancer factor 2C
NRG1neuregulin 1
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CDH2CDH2cadherin 2, type 1, N-cadherin (neuronal)
MEG3MEG3maternally expressed 3 (non-protein coding)
MEF2CMEF2Cmyocyte enhancer factor 2C
NRG1NRG1neuregulin 1

Troyanskaya Laboratory - Princeton University