ASD

GO:0048665 neuron fate specification (22)

GeneInput weightStandardRank
NTRK30.2514
ASCL1--229
POU4F1--292
PAX60.251355
NKX2-2--771
ISL1--1441
FOXA2--1835
FOXA1--2277
HOXD10--2845
NKX6-1--3174
HOXC10--4404
LBX1--5371
NKX6-2--5422
TLX3--5583
GLI2--15731
MNX1--5932
GSX2--6242
GLI3--19032
ATOH1--9258
FOXA3--9582
EVX1--12405
SHH--115942

Network

GO:0048665

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
POU4F1POU class 4 homeobox 1 Entrez:5457  Ensembl: ENSG00000152192  HGNC: 9218  HPRD: 03379 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
NKX2-2NK2 homeobox 2 Entrez:4821  Ensembl: ENSG00000125820  HGNC: 7835  HPRD: 05213 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU class 4 homeobox 1
PAX6paired box 6
NKX2-2NK2 homeobox 2
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU4F1POU class 4 homeobox 1
PAX6PAX6paired box 6
NKX2-2NKX2-2NK2 homeobox 2

Troyanskaya Laboratory - Princeton University