ASD

GO:0009895 negative regulation of catabolic process (56)

GeneInput weightStandardRank
CNR10.25110
GRIN2A0.25156
AKT10.251303
ADORA1--498
HDAC4--963
FLNA--1984
PRKCG--11280
FYN--1284
RELA--1352
BAG6--1435
SMAD3--1541
ADRA2A0.2511556
AGAP2--1884
TIMP1--2285
GSK3A--2346
HSP90AB1--2440
SERPINE2--2896
SMAD4--2927
PDE3B--3088
DDIT4--3214
USP44--3386
N4BP1--3558
KIAA0226--4470
CST3--14680
FURIN--4868
PTPN3--5124
HTR2B--5233
CIDEA--5234
TAF9--5472
SERPINB12--5630
PPARA--5743
ADRA1B0.2515964
GRIN2C--6011
IL1B--16220
DAP--6553
NOS20.2517024
GIMAP5--7409
IL10--17883
MAD2L2--11317
HCAR2--12026
APOA2--12739
CLN3--113525
PABPC1--13951
IRAK3--14013
HP--14183
GIPC1--15140
MTOR--15435
SHH--115942
INS--119021
APOC3--19472
TNF0.25119823
TIMP3--20931
MDM4--21248
APOC1--21328
UBXN1--22532
MAD2L1--22813

Network

GO:0009895

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
AKT1v-akt murine thymoma viral oncogene homolog 1
ADORA1adenosine A1 receptor
HDAC4histone deacetylase 4
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
ADORA1ADORA1adenosine A1 receptor
HDAC4HDAC4histone deacetylase 4

Troyanskaya Laboratory - Princeton University