ASD

GO:0048742 regulation of skeletal muscle fiber development (27)

GeneInput weightStandardRank
PLCB1--161
MEG3--201
HDAC4--963
SOX9--11045
PIK3R10.2511065
BTG1--1268
SHOX2--2149
MUSK--2237
HDAC5--2683
ILK--2917
NOTCH1--13360
HDAC9--3770
RBM24--3835
TBX3--3843
SOX8--4770
BMP4--15180
NKX2-50.2515490
AGRN0.2515611
MYOCD--5769
BOC--6380
NEU2--6474
MBNL3--10153
ZFHX3--110438
NMRK2--11469
RBM38--12396
IGFBP3--13922
FBXO22--24394

Network

GO:0048742

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
SOX9SRY (sex determining region Y)-box 9 Entrez:6662  HPRD: 06427  HGNC: 11204  Ensembl: ENSG00000125398 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3maternally expressed 3 (non-protein coding)
HDAC4histone deacetylase 4
SOX9SRY (sex determining region Y)-box 9
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3MEG3maternally expressed 3 (non-protein coding)
HDAC4HDAC4histone deacetylase 4
SOX9SOX9SRY (sex determining region Y)-box 9
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Troyanskaya Laboratory - Princeton University