ASD

GO:0006140 regulation of nucleotide metabolic process (349)

GeneInput weightStandardRank
GNAO1--3
NTRK20.25128
GABBR20.25141
PLCB1--161
RGS70.25180
ADNP0.5191
RGS4--99
ADCY2--102
AMPH--118
ADCYAP1--127
PGAM1--139
GRM70.251147
SSTR2--185
SFRP1--204
PAFAH1B10.251208
ABR--211
RASGRF1--213
CRHR1--280
NF10.251333
APLP1--335
GABBR10.251352
RGS6--375
GRM3--399
DNAJB6--407
PTPRN20.251441
CALCA--460
ADCY10.251466
MAP2K10.251474
DRD50.251482
GNAQ--490
ADORA1--498
RGS11--567
NPY2R0.251597
GNAZ--618
JUN--647
FSHR--1648
DRD10.251662
GUCA1A--1762
OPRK10.251764
DGKI--807
AGAP10.251833
RABGAP1--856
GNAL--860
ADRB1--866
SIPA1L1--893
GRIK30.251976
FLNA--1984
THY1--993
FGD1--11009
NPY1R0.2511012
CAP1--1037
RAPGEF2--1064
DLC1--1105
ARHGAP5--1129
ADCYAP1R1--1132
GRM80.2511152
NDEL10.2511194
RAP1GAP--1195
CAP2--1213
PTHLH--11269
RABGAP1L--1270
EDNRB--11322
VIPR2--1327
GNAI3--1340
PALM--1349
GRM2--1421
RGS17--1439
AKAP5--1517
HTR70.2511529
ELMOD1--1534
SPRY2--1552
ADRA2A0.2511556
GSK3B--1592
GNAI1--1613
ALDOB--1669
HTR1A0.2511672
ARHGAP35--1706
GUCY1A3--1730
ADRB3--11787
TSC10.2511844
AGAP2--1884
ADCY8--1906
MC2R--1919
MCHR10.2512005
DOCK40.2512053
DRD20.2512071
CHN2--2211
PREX1--2219
CALCR--2247
RAP1GDS1--2274
CHRM50.2512290
GHRHR--2312
GSK3A--2346
GNAS--12352
LHCGR0.2512362
RALGAPA1--2363
ADCY9--2435
PREX2--2459
RASAL2--2472
STMN3--2549
RANGAP1--2553
ASAP2--2554
RGS5--2560
FZD10--2606
GIT1--2627
CDKL5--12680
ABCA1--12698
RHOG--2753
DRD30.2512757
DOCK1--2785
TBC1D10B--2796
BCR--12801
HTR4--2810
WNT5A--2870
RXFP1--2904
S1PR1--2910
RGS16--2915
RGS20--2998
SPECC1L--3048
RASAL1--3061
TSHR--3078
GNG7--3138
AKAP12--3150
SOS1--13181
PTK2B--3191
SMAP1--3205
CALCRL0.2513258
OPRD10.2513266
EDNRA--13271
MC4R0.2513280
MC5R--3358
RGS12--3374
GCGR--13430
ARHGAP26--13447
DAB2IP--3635
SYNGAP10.2513673
RGS2--3677
ARHGAP1--3707
NPR3--3798
BCL6--3994
VAV3--4024
AGAP3--4033
CBS0.2514080
RGS9--4146
RASA1--4166
ACR--4233
MYO9B--4244
BIN1--4255
DYNLT1--4275
GCG--4286
ARAP2--4306
ADCY5--4352
ADCY6--4362
FGF10--14373
ARFGAP1--4379
GPR3--4384
CHRM4--4460
ARHGAP6--4472
P2RY1--4483
AIPL1--14495
WNT11--4528
AVPR2--14537
GHRH--4568
RGS8--4592
ADCY3--4618
CASR--4724
PXK--4731
ADORA3--4733
AHSA1--4767
NTRK10.2514883
MRAP2--4941
ARHGAP29--4961
RGS22--5110
FOXJ1--5202
HTR2B--5233
ASAP1--5458
PTH--5481
BVES--5536
HTR1B0.2515751
GRM4--5804
TNNT2--15818
AXIN2--15927
GALR1--5954
GPR26--6001
ALS2CR12--6098
ARAP3--6203
MYBPC3--16241
MC3R0.2516322
CXCL13--6358
RXFP2--16360
GNAI2--6384
ARL2--6405
S1PR3--6584
RGS13--6632
GRHL3--6732
RALGAPA2--6758
TBCD--6876
RGS18--6917
BNIP2--6921
CCL11--7037
DRD40.2517058
RGN--7142
RASGRP3--7172
GLP1R--7291
RGS1--7315
ERRFI1--7414
NPPC--7442
MLST8--7510
RAPGEF6--7525
SNX18--7859
PIN1--8222
OPRL10.2518293
MC1R--18333
ADCY4--8354
TAX1BP3--8734
GUCA2B--8899
FGD3--9083
SSTR50.2519084
ACAP3--9115
MYH6--19135
GIPR--9148
PTGDR2--9477
SYDE1--9488
EDN1--9566
ADAP1--9576
ADORA2A0.2519605
UCN3--9836
RALBP1--10248
SYDE2--10285
SMAP2--10497
SPRY1--10579
MRAP--10738
AXIN1--110905
GUCA1B--10950
ADORA2B--11164
RGS14--11308
CORT--11364
TSC20.25111448
INSL3--111614
AVP--111615
FGD4--111677
CCL19--11890
TBC1D15--12177
ALS2--112325
PDZD3--12463
RGS19--12486
AGAP11--12524
ARHGAP8--12529
ARHGEF10--12556
ARHGEF19--12571
AGAP7--12689
NOS3--12710
GALR2--12784
RP2--112866
ARHGEF6--13050
LTB4R2--13227
LRRK2--113335
RASAL3--13407
FGD5--13516
RGS21--13538
SNX9--13625
RASA4--13696
MYL3--113896
FZD2--13981
ASAP3--14066
EPHA2--114150
ALDH1A1--14295
TNNI3--114741
ARHGAP15--14909
RASA2--15169
PDE6D--15374
ADM2--15430
MTOR--15435
FGD6--15723
AGAP4--15746
GALR3--15944
OPHN10.5116404
AGAP10--17449
AGFG1--17498
CCL24--17974
P2RY11--18359
CTGLF11P--18607
FGD2--18783
ARRB1--19005
AGAP9--19043
CCL21--19130
GPR78--19507
CDC42EP2--19516
AGAP5--19774
AJUBA--19840
ARHGAP9--19961
CCL26--19975
OXER1--20000
GPR65--20238
IQGAP1--20290
GNA13--20348
ARHGEF16--20461
DOCK7--20528
AGFG2--20529
RASA3--20776
ARFGAP2--20834
AGAP6--21024
APOE0.25121310
CCR7--21314
RAB3GAP2--21401
ADAP2--21582
ARHGAP4--21597
ELMOD2--21756
AGAP8--21764
SLC9A3R1--21807
FICD--21845
RGS3--21940
GMIP--22058
SIPA1--22102
RAB3GAP1--22229
ARHGEF10L--22238
CCR2--22318
S1PR4--22365
ACAP2--22442
ATPIF1--22467
RGS10--22712
ADRB20.25122718
PTPLAD1--22865
GNB2L1--22873
TNNC1--122986
VAV1--23026
TIMP2--23119
CDA--23240
SNX13--23361
NCKAP1L--23440
TPM1--123549
TBC1D2--23630
TNNT3--123680
GABARAPL2--23840
GIT2--23867
RACGAP1--24138
DNAJC1--24196
ARHGAP27--24221
RALGAPB--24333
NPR1--24360
SCRIB--24455
ADCY7--25198
ACAP1--25394
ARFGAP3--25402
ARAP1--25493
TPM2--125528
MYL4--25557
OXA1L--25770
DNAJC10--25801

Network

GO:0006140

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 Entrez:9568  Ensembl: ENSG00000136928  HGNC: 4507  HPRD: 09552 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
RGS7regulator of G-protein signaling 7 Entrez:6000  HGNC: 10003  HPRD: 03948  Ensembl: ENSG00000182901 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NTRK2neurotrophic tyrosine kinase, receptor, type 2
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RGS7regulator of G-protein signaling 7
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
GABBR2GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RGS7RGS7regulator of G-protein signaling 7

Troyanskaya Laboratory - Princeton University