ASD

GO:0007265 Ras protein signal transduction (124)

GeneInput weightStandardRank
GNB1--15
YWHAB0.25145
ARHGDIA--76
KRAS--1143
SHC3--330
NF10.251333
MAP2K10.251474
G3BP2--608
RAP2A--652
ADRB1--866
ARHGEF11--870
RHOA--973
SHOC2--974
MAPK1--985
MAP2K20.2511066
CDH13--1072
MCF2L--1084
ARHGAP5--1129
MAPK11--1258
ELMO1--1381
ULK1--1530
ADRA2A0.2511556
SRGAP1--1805
VANGL2--1957
IGF10.2511993
CFL1--1997
SHC2--2147
SRC--2241
RHOB--2589
GRB2--2662
ABCA1--12698
RHOG--2753
RALGDS--2833
AGTR1--12898
RASGRP10.2512942
RAP2C--3043
RALB--3082
SOS1--13181
EDNRA--13271
KSR1--3401
MAPKAPK2--3441
RB1--13450
LIMK1--3487
ARHGAP1--3707
NGF0.2513749
NISCH--3766
MYO9B--4244
ARHGEF3--4334
ARHGAP6--4472
CDKN1A--4620
MAPK14--4729
NTRK10.2514883
ARHGAP29--4961
ROCK1--5154
RALA--5445
PTH--5481
NRAS--15506
CELSR1--5539
RAF10.2515559
RREB1--5698
ARHGDIG--5782
SHC1--5839
MAPK30.2516096
MRAS--6204
CRKL--6254
RHOJ--7171
RASGRP3--7172
RAPGEF6--7525
PLCE1--7692
TAX1BP3--8734
FGF2--9627
CDKN2A--19650
GRAP2--9710
CDC42EP4--10134
DHCR24--10169
ARHGDIB--10220
RHOU--10428
FARP2--10651
USP8--10732
GNA12--10962
SDCBP--11081
RTKN--11331
RSU1--11650
APOA1--111900
RASGRP2--12257
CDC42EP5--12367
HRAS0.25112845
ROPN1B--13977
IQGAP3--14020
CDC42EP1--14308
DBNL--14433
RAP2B--15525
COL1A2--119210
APOC3--19472
RGL2--19609
WASF2--19696
MAPK12--19748
PLD1--19789
GNA13--20348
DOK3--20488
CTNNAL1--20656
DOK2--20868
RRAS2--21264
APOE0.25121310
ARHGAP4--21597
TP530.25121968
GRAP--22017
RFXANK--122485
RASSF1--22618
LAT--22661
PTPLAD1--22865
SGSM3--22884
CNKSR1--23252
MAPK13--23617
MAPKAPK3--23643
CDK1--24001
CDK2--24011
DOK1--24151
ARHGEF1--24198
RRAS--24498
G3BP1--24617
RHOD--25325
BRAP--25341
CCNA2--25594

Network

GO:0007265

Network
Enrichment
NameDescriptionExternal IDs
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
ARHGDIARho GDP dissociation inhibitor (GDI) alpha Entrez:396  HGNC: 678  Ensembl: ENSG00000141522  HPRD: 03565 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
SHC3SHC (Src homology 2 domain containing) transforming protein 3 Entrez:53358  HPRD: 12005  HGNC: 18181 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ARHGDIARho GDP dissociation inhibitor (GDI) alpha
KRASKirsten rat sarcoma viral oncogene homolog
SHC3SHC (Src homology 2 domain containing) transforming protein 3
Query geneGeneGene descriptionEdge score
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ARHGDIAARHGDIARho GDP dissociation inhibitor (GDI) alpha
KRASKRASKirsten rat sarcoma viral oncogene homolog
SHC3SHC3SHC (Src homology 2 domain containing) transforming protein 3

Troyanskaya Laboratory - Princeton University