ASD

GO:0001843 neural tube closure (46)

GeneInput weightStandardRank
PFN1--74
SFRP1--204
LHX2--362
SALL1--408
PAX2--459
LRP6--778
DLC1--1105
PTCH1--11149
LMO4--1406
ZIC2--11550
TSC10.2511844
OPA1--1951
VANGL2--1957
ENAH--1958
TFAP2A--12460
T--2584
WNT5A--2870
DEAF1--2911
ALX1--2966
COBL0.2513131
FZD3--3579
SFRP2--3758
SKI--4231
ZEB2--4607
RGMA--4651
BMP4--15180
CELSR1--5539
IFT122--16114
TWIST1--16128
TGIF1--16785
VASP--8124
TULP3--8569
KDM2B--8663
SALL4--9465
SUFU--19989
BBS4--110693
FUZ--10698
ADM--10761
TSC20.25111448
DVL2--12293
TEAD2--19457
FZD6--19825
PTK7--20787
KAT2A--22874
BCL10--124165
LIAS--25118

Network

GO:0001843

Network
Enrichment
NameDescriptionExternal IDs
PFN1profilin 1 Entrez:5216  Ensembl: ENSG00000108518  HGNC: 8881  HPRD: 01452 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
LHX2LIM homeobox 2 Entrez:9355  HPRD: 04786  HGNC: 6594  Ensembl: ENSG00000106689 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PFN1profilin 1
SFRP1secreted frizzled-related protein 1
LHX2LIM homeobox 2
SALL1sal-like 1 (Drosophila)
PAX2paired box 2
Query geneGeneGene descriptionEdge score
PFN1PFN1profilin 1
SFRP1SFRP1secreted frizzled-related protein 1
LHX2LHX2LIM homeobox 2
SALL1SALL1sal-like 1 (Drosophila)
PAX2PAX2paired box 2

Troyanskaya Laboratory - Princeton University