ASD

GO:0002088 lens development in camera-type eye (46)

GeneInput weightStandardRank
SOX11--66
PAX60.251355
MEIS1--566
SHROOM2--763
PROX1--962
HIPK1--1034
WNT2B--1126
PVRL3--1288
SMAD3--1541
FGFR3--11648
SIX3--11742
WNT20.2511783
HIPK2--2306
CRYGC--2441
PVRL1--2493
WNT5A--2870
FOXE3--13264
FOXE1--13384
CDON--3482
CRYGA--3857
FZR1--3987
CRYBA1--4008
SKIL--4016
SKI--4231
NF2--14798
SLC7A11--4816
BMP4--15180
MIP--5384
BFSP2--5589
CTNNB10.2516229
WNT7A--6375
BFSP1--6548
CRYAA--6901
CRYGB--7181
GJA8--7422
WNT7B--7693
DLG1--10557
CRYGS--10592
PYGO2--11582
WNT5B--11732
PITX30.25112815
TGFB10.25114736
TDRD7--20596
SIX5--122607
CASP6--24423
CRYAB--124949

Network

GO:0002088

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
MEIS1Meis homeobox 1 Entrez:4211  HGNC: 7000  Ensembl: ENSG00000143995  HPRD: 03442 
SHROOM2shroom family member 2 Entrez:357  Ensembl: ENSG00000146950  HGNC: 630  HPRD: 02113 
PROX1prospero homeobox 1 Entrez:5629  HPRD: 03330  HGNC: 9459  Ensembl: ENSG00000117707 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
PAX6paired box 6
MEIS1Meis homeobox 1
SHROOM2shroom family member 2
PROX1prospero homeobox 1
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
PAX6PAX6paired box 6
MEIS1MEIS1Meis homeobox 1
SHROOM2SHROOM2shroom family member 2
PROX1PROX1prospero homeobox 1

Troyanskaya Laboratory - Princeton University