ASD

GO:0051403 stress-activated MAPK cascade (53)

GeneInput weightStandardRank
MAPK10--1194
MEF2C0.251248
MAP2K10.251474
MAP2K4--579
JUN--647
RPS6KA5--677
RPS6KA20.251711
RPS6KA3--861
MAPK1--985
CREB1--991
MAP2K20.2511066
ATF2--1137
MAPK11--1258
ELK1--1329
MAPK8--1764
FOS--1839
DUSP6--1889
MAP3K7--2169
MAPK9--2324
TAOK20.2512490
TAB2--2777
MAPKAPK2--3441
AGT--13783
DUSP4--4300
MAPK7--4626
MAPK14--4729
UBC--5781
DUSP3--5845
MEF2A--6060
MAPK30.2516096
TAB3--6412
DUSP7--7411
RBM4--8366
MAP2K7--8382
MAP2K3--9005
IRAK1--9309
TAB1--9783
MAP2K6--10398
IRAK2--11461
RIPK2--13928
TRAF6--14847
ATF1--15773
CCM2--20854
RPS6KA1--22219
UBB--22223
NOD2--122677
RPS27A--22920
MAPKAPK3--23643
NOD1--23711
IKBKG--123817
CDK1--24001
UBA52--24116
CRYAB--124949

Network

GO:0051403

Network
Enrichment
NameDescriptionExternal IDs
MAPK10mitogen-activated protein kinase 10 Entrez:5602  HGNC: 6872  Ensembl: ENSG00000109339  HPRD: 04207 
MEF2Cmyocyte enhancer factor 2C Entrez:4208  HGNC: 6996  Ensembl: ENSG00000081189  HPRD: 02809 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
MAP2K4mitogen-activated protein kinase kinase 4 Entrez:6416  HPRD: 03213  Ensembl: ENSG00000065559  HGNC: 6844 
JUNjun proto-oncogene Entrez:3725  HGNC: 6204  HPRD: 01302  Ensembl: ENSG00000177606 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPK10mitogen-activated protein kinase 10
MEF2Cmyocyte enhancer factor 2C
MAP2K1mitogen-activated protein kinase kinase 1
MAP2K4mitogen-activated protein kinase kinase 4
JUNjun proto-oncogene
Query geneGeneGene descriptionEdge score
MAPK10MAPK10mitogen-activated protein kinase 10
MEF2CMEF2Cmyocyte enhancer factor 2C
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
MAP2K4MAP2K4mitogen-activated protein kinase kinase 4
JUNJUNjun proto-oncogene

Troyanskaya Laboratory - Princeton University