ASD

GO:0008589 regulation of smoothened signaling pathway (38)

GeneInput weightStandardRank
FGFR2--1165
SFRP1--204
RUNX2--1209
FGF9--241
SALL1--408
CHRD--697
ZIC1--774
PTCH1--11149
OTX2--11295
PRRX1--1491
SALL3--1561
FGFR3--11648
SHOX2--2149
POR0.2512359
HHIP--2403
SERPINE2--2896
FGF10--14373
IHH--14742
GPC3--15153
C2CD3--5468
SMO0.2515864
GAS1--5960
GLI1--6597
WNT7B--7693
KIF7--17773
CD3E--8226
TULP3--8569
GLI3--19032
SUFU--19989
FUZ--10698
CTNNA1--11705
WNT9A--14123
SHH--115942
RPGRIP1L--19545
RAB23--21919
STK36--22089
DISP1--23291
PRRX2--23414

Network

GO:0008589

Network
Enrichment
NameDescriptionExternal IDs
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RUNX2runt-related transcription factor 2 Entrez:860  Ensembl: ENSG00000124813  HGNC: 10472  HPRD: 02566 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FGFR2fibroblast growth factor receptor 2
SFRP1secreted frizzled-related protein 1
RUNX2runt-related transcription factor 2
FGF9fibroblast growth factor 9
SALL1sal-like 1 (Drosophila)
Query geneGeneGene descriptionEdge score
FGFR2FGFR2fibroblast growth factor receptor 2
SFRP1SFRP1secreted frizzled-related protein 1
RUNX2RUNX2runt-related transcription factor 2
FGF9FGF9fibroblast growth factor 9
SALL1SALL1sal-like 1 (Drosophila)

Troyanskaya Laboratory - Princeton University