ASD

GO:0009755 hormone-mediated signaling pathway (31)

GeneInput weightStandardRank
NR3C1--463
THRA--485
NR4A3--1594
NR2E10.251699
BMP7--987
ESR20.2511484
NR3C2--1684
NR1D1--1801
ESR10.2511914
GHSR0.2512085
TRH--2296
LHCGR0.2512362
PGR--2715
LATS1--3031
GCGR--13430
ASIP--3926
KDM3A--4222
BMP4--15180
ADIPOR2--5403
CUZD1--5600
PPARA--5743
AGRP0.2516721
GHRL0.2519333
NUP62--19343
NR2C1--9554
PPARD--9856
GHR--110058
LATS2--15008
ADIPOR1--15130
NR2F6--20967
PGRMC2--23104

Network

GO:0009755

Network
Enrichment
NameDescriptionExternal IDs
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
THRAthyroid hormone receptor, alpha Entrez:7067  HGNC: 11796  Ensembl: ENSG00000126351  HPRD: 07185 
NR4A3nuclear receptor subfamily 4, group A, member 3 Entrez:8013  Ensembl: ENSG00000119508  HGNC: 7982  HPRD: 02766 
NR2E1nuclear receptor subfamily 2, group E, member 1 Entrez:7101  Ensembl: ENSG00000112333  HGNC: 7973  HPRD: 07230 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
THRAthyroid hormone receptor, alpha
NR4A3nuclear receptor subfamily 4, group A, member 3
NR2E1nuclear receptor subfamily 2, group E, member 1
BMP7bone morphogenetic protein 7
Query geneGeneGene descriptionEdge score
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
THRATHRAthyroid hormone receptor, alpha
NR4A3NR4A3nuclear receptor subfamily 4, group A, member 3
NR2E1NR2E1nuclear receptor subfamily 2, group E, member 1
BMP7BMP7bone morphogenetic protein 7

Troyanskaya Laboratory - Princeton University