ASD

GO:0042475 odontogenesis of dentine-containing tooth (44)

GeneInput weightStandardRank
PDGFRA--1233
EDA--1615
LRP6--778
BMP7--987
BCL11B--1127
DLX20.2511235
LRP4--1290
BSG--1355
HDAC2--1413
LEF1--1731
BMPR1A--2059
MSX1--12365
DLX10.2512366
AMBN--2369
SOSTDC1--2578
WNT6--2891
AMELX--12925
LHX8--3040
ACVR2B--13179
ODAM--4109
FGF10--14373
NF2--14798
FGF4--4827
BMP4--15180
HDAC1--5284
BCL2L11--5454
NKX2-3--5540
GLI2--15731
SMO0.2515864
CTNNB10.2516229
WNT7B--7693
EDAR--17761
FST--8021
GLI3--19032
ADM--10761
CTNNA1--11705
AMTN--12408
GATA6--113349
SHH--115942
LAMA5--19186
CA2--120831
ITGA6--21003
FOXC1--122868
TP63--124113

Network

GO:0042475

Network
Enrichment
NameDescriptionExternal IDs
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
EDAectodysplasin A Entrez:1896  HPRD: 02347  Ensembl: ENSG00000158813  HGNC: 3157 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) Entrez:64919  HGNC: 13222  Ensembl: ENSG00000127152  HPRD: 05950 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
EDAectodysplasin A
LRP6low density lipoprotein receptor-related protein 6
BMP7bone morphogenetic protein 7
BCL11BB-cell CLL/lymphoma 11B (zinc finger protein)
Query geneGeneGene descriptionEdge score
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
EDAEDAectodysplasin A
LRP6LRP6low density lipoprotein receptor-related protein 6
BMP7BMP7bone morphogenetic protein 7
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)

Troyanskaya Laboratory - Princeton University