ASD

GO:0035023 regulation of Rho protein signal transduction (139)

GeneInput weightStandardRank
KALRN--63
CDH2--130
ARHGEF4--203
SFRP1--204
PAFAH1B10.251208
ABR--211
RASGRF1--213
TRIO--246
TIAM1--369
ARHGEF12--1444
ARHGEF7--492
ARHGEF9--1639
JUN--647
MCF2--650
ARHGEF11--870
ADRA1A--937
THY1--993
FGD1--11009
MCF2L--1084
RAC1--1087
DLC1--1105
ARHGAP5--1129
NDEL10.2511194
FARP1--1520
GSK3B--1592
ITSN1--1679
ARHGAP35--1706
TSC10.2511844
DOCK40.2512053
PREX1--2219
TNFAIP1--2377
PREX2--2459
RASGRF2--2464
STMN3--2549
SOS2--2569
CUL30.512576
FZD10--2606
CDKL5--12680
ARHGEF2--2743
RHOG--2753
TIAM2--2771
VAV2--2783
BCR--12801
LPAR1--2975
SOS1--13181
PTK2B--3191
ARHGAP26--13447
ARHGEF38--3547
ARHGAP1--3707
PLEKHG3--3981
BCL6--3994
VAV3--4024
KCTD130.2514138
ITSN2--4156
MYO9B--4244
DYNLT1--4275
ARHGEF3--4334
ARHGEF17--4415
ARHGAP6--4472
AKAP13--4708
ARHGAP29--4961
FOXJ1--5202
BVES--5536
ARHGEF26--5983
ARAP3--6203
GRHL3--6732
ABRA--6916
CCL11--7037
MCF2L2--7202
ARHGEF40--7278
GPR55--7357
ERRFI1--7414
MLST8--7510
NET1--7744
NGEF--7891
PIN1--8222
ARHGEF25--8403
ARHGEF18--8718
TAX1BP3--8734
FGD3--9083
SYDE1--9488
PLEKHG2--10000
RALBP1--10248
SYDE2--10285
FARP2--10651
PLEKHG4B--11251
FGD4--111677
ARHGEF33--11746
ARHGEF15--11779
SPATA13--11820
CCL19--11890
DNMBP--12168
PLEKHG5--12196
ALS2--112325
F2R--12498
ARHGAP8--12529
ARHGEF10--12556
ARHGEF19--12571
ECT2L--12620
SCAI--12809
ARHGEF6--13050
PLEKHG7--13455
FGD5--13516
EPHA2--114150
ARHGEF39--14425
LPAR2--14606
ARHGAP15--14909
F2RL1--15088
MTOR--15435
FGD6--15723
OPHN10.5116404
CCL24--17974
FGD2--18783
ARRB1--19005
CCL21--19130
CDC42EP2--19516
PLEKHG1--19763
ARHGEF37--19952
CCL26--19975
GPR65--20238
ARHGEF16--20461
DOCK7--20528
PLEKHG4--21231
CCR7--21314
ARHGAP4--21597
OBSCN--21654
FICD--21845
GMIP--22058
ARHGEF10L--22238
PLEKHG6--22935
VAV1--23026
NCKAP1L--23440
ARHGEF5--23550
ARHGEF1--24198
ARHGAP27--24221
SCRIB--24455
ECT2--24948
ARAP1--25493
ALS2CL--25806

Network

GO:0035023

Network
Enrichment
NameDescriptionExternal IDs
KALRNkalirin, RhoGEF kinase Entrez:8997  HPRD: 06859  HGNC: 4814  Ensembl: ENSG00000160145 
CDH2cadherin 2, type 1, N-cadherin (neuronal) Entrez:1000  Ensembl: ENSG00000170558  HGNC: 1759  HPRD: 00226 
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4 Entrez:50649  Ensembl: ENSG00000136002  HGNC: 684  HPRD: 05559 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KALRNkalirin, RhoGEF kinase
CDH2cadherin 2, type 1, N-cadherin (neuronal)
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4
SFRP1secreted frizzled-related protein 1
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Query geneGeneGene descriptionEdge score
KALRNKALRNkalirin, RhoGEF kinase
CDH2CDH2cadherin 2, type 1, N-cadherin (neuronal)
ARHGEF4ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4
SFRP1SFRP1secreted frizzled-related protein 1
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)

Troyanskaya Laboratory - Princeton University