ASD

GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (119)

GeneInput weightStandardRank
SOX11--66
SFRP1--204
NREP--435
NR3C1--463
ACVR1B--510
PEG10--540
FKBP1A--605
TRIM33--1692
CHRD--697
PCSK6--731
BMPR2--1964
BMP7--987
SMAD7--1283
FBN2--1425
ONECUT2--1475
SMAD3--1541
ACVR2A--1768
STRAP--1862
CITED1--1867
GDF6--11929
BMPR1A--2059
SMAD6--2079
HIPK2--2306
LEMD3--12358
NKX2-1--2488
SOSTDC1--2578
SMURF2--2642
GREM1--2654
WNT5A--2870
ILK--2917
SMAD4--2927
ITGA8--3151
ACVR2B--13179
BMP10--3196
BMP6--3242
WNT1--3263
BMPER--3267
NOTCH1--13360
CITED2--3457
HOXA13--3602
BMP2--13686
SFRP2--3758
HES5--4001
SKIL--4016
SKI--4231
ADAMTSL2--4249
FGF10--14373
RGMA--4651
SMURF1--4696
CDKN1C--14821
FURIN--4868
GPC3--15153
BMP4--15180
CER1--5192
CIDEA--5234
FOXD1--5256
TGFB3--15321
BCL9L--5421
FOXD2--5493
HES10.2515662
SOST--5795
PRDM16--5921
TGFBR1--16027
FBN1--16138
ZNF703--6470
MEN1--16723
DKK1--6892
SMAD2--7224
FOXD4L1--7290
CHST11--7380
GDF7--7494
BAMBI--7548
NOG--17650
NPNT--7660
FST--8021
PIN1--8222
IL17F--8673
TGFBR3--8717
INHBA--9731
FOXD4--9835
ASPN--10001
VWC2--10359
FOXD4L4--10472
ADAM17--11074
GATA4--111137
STK11--111332
ACVR1--111780
GDF2--11942
DAND5--12393
SKOR2--13004
GATA6--113349
HSPA5--13639
ACVRL1--114027
FBXL15--14570
TGFB10.25114736
GIPC1--15140
CDKN2B--15696
RBPMS--16365
SKOR1--16408
FOXD4L5--16935
ENG--117647
FOXD4L2--17995
FOXD4L6--19463
CYR61--19764
ING2--21012
POU5F1--21422
THBS1--21993
FZD1--22086
EID2--22443
GLG1--22724
TGFB1I1--22730
WWTR1--22777
SNX6--22785
LTBP1--23598
FSTL3--24700
CAV1--124767
LTBP4--25140
TWSG1--25171
TTK--25644

Network

GO:0090092

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
NREPneuronal regeneration related protein Entrez:9315  HGNC: 16834  HPRD: 09545  Ensembl: ENSG00000134986 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
ACVR1Bactivin A receptor, type IB Entrez:91  Ensembl: ENSG00000135503  HGNC: 172  HPRD: 03193 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
SFRP1secreted frizzled-related protein 1
NREPneuronal regeneration related protein
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ACVR1Bactivin A receptor, type IB
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
SFRP1SFRP1secreted frizzled-related protein 1
NREPNREPneuronal regeneration related protein
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ACVR1BACVR1Bactivin A receptor, type IB

Troyanskaya Laboratory - Princeton University