ASD

GO:0050433 regulation of catecholamine secretion (32)

GeneInput weightStandardRank
CNR10.25110
HTR2A0.25151
GABBR10.251352
SNCA--1401
CARTPT0.2511181
ADRA2A0.2511556
CHRNA40.2511580
CHRNA70.511657
RTN4--1776
DRD20.2512071
SLC18A1--2477
DRD30.2512757
CHRNA6--2934
SPECC1L--3048
SNCG--3377
AGT--13783
GDNF--14462
P2RY1--4483
OXTR0.514494
ADRBK1--4864
HTR1B0.2515751
ADRA2C--6524
CXCL12--7204
ADRA2B--8196
PINK1--18983
ADORA2A0.2519605
OXT0.25110022
ADORA2B--11164
C5--115436
CHRNB20.25120277
CHRFAM7A--21295
PTGS1--23458

Network

GO:0050433

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1 Entrez:2550  HGNC: 4070  Ensembl: ENSG00000204681  HPRD: 04644 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
CARTPTCART prepropeptide Entrez:9607  HGNC: 24323  HPRD: 04006  Ensembl: ENSG00000164326 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
CARTPTCART prepropeptide
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GABBR1GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
CARTPTCARTPTCART prepropeptide

Troyanskaya Laboratory - Princeton University