ASD

GO:0045995 regulation of embryonic development (57)

GeneInput weightStandardRank
PLCB1--161
MEG3--201
NIPBL--1561
LRP6--778
AMOT--933
BMP7--987
WNT2B--1126
OTX2--11295
SEPT7--1489
AR0.2511499
WNT20.2511783
FOXA2--1835
DUSP6--1889
LHX1--1926
VANGL2--1957
BMPR1A--2059
NODAL--12184
FGFR1--2550
FZD7--2714
WNT5A--2870
GATA3--3207
NOTCH1--13360
SOX17--3484
LAMA1--3639
SFRP2--3758
FGF10--14373
DVL3--4438
GDNF--14462
SIX4--4623
ADIPOQ0.2514834
BMP4--15180
LAMA4--5646
OSR1--6192
IL1B--16220
CTNNB10.2516229
GRHL3--6732
NFE2L2--6933
TBX18--7034
SNAI1--8474
HNF1B--19562
MESP1--10948
RBM19--10966
INSR--110986
LAMA2--111986
LAMA3--12078
E4F1--12260
HNF4A--112281
DVL2--12293
SIX1--115117
SHH--115942
OSR2--18904
DVL1P1--19166
LAMA5--19186
TNF0.25119823
DVL1--21155
WDPCP--121335
GNB2L1--22873

Network

GO:0045995

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
NIPBLNipped-B homolog (Drosophila) Entrez:25836  HPRD: 10560  HGNC: 28862  Ensembl: ENSG00000164190 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
AMOTangiomotin Entrez:154796  HGNC: 17810  Ensembl: ENSG00000126016  HPRD: 02327 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3maternally expressed 3 (non-protein coding)
NIPBLNipped-B homolog (Drosophila)
LRP6low density lipoprotein receptor-related protein 6
AMOTangiomotin
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3MEG3maternally expressed 3 (non-protein coding)
NIPBLNIPBLNipped-B homolog (Drosophila)
LRP6LRP6low density lipoprotein receptor-related protein 6
AMOTAMOTangiomotin

Troyanskaya Laboratory - Princeton University