ASD

GO:0014072 response to isoquinoline alkaloid (23)

GeneInput weightStandardRank
GNAO1--3
CNR10.25110
PRKCE--156
GRIN1--167
TAC10.251543
PCSK1--604
PPP2R2A--1304
RELA--1352
DRD20.2512071
PEA15--2463
TAC3--2507
TACR3--2526
DRD30.2512757
EDNRA--13271
CYP19A10.2513314
PLCG1--5952
ADRA1B0.2515964
IL1B--16220
TACR1--7688
GHR--110058
SRR--21028
CCL5--21529
ADA0.5124175

Network

GO:0014072

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
TAC1tachykinin, precursor 1 Entrez:6863  HGNC: 11517  HPRD: 08876  Ensembl: ENSG00000006128 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
PRKCEprotein kinase C, epsilon
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
TAC1tachykinin, precursor 1
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
PRKCEPRKCEprotein kinase C, epsilon
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
TAC1TAC1tachykinin, precursor 1

Troyanskaya Laboratory - Princeton University