ASD

GO:0043484 regulation of RNA splicing (42)

GeneInput weightStandardRank
AFF20.25113
TRA2B--65
SON--455
DDX5--506
PTBP1--583
CELF3--607
SRSF9--797
KHDRBS3--961
SRRM4--1068
MBNL1--1113
RBM5--1665
MBNL2--1747
CELF4--1983
SRSF10--2264
MYOD1--2280
RBMX--2432
SRSF12--2655
AKT2--13025
CELF6--3255
SRSF7--3630
SRSF4--4276
SNRNP70--4833
RBM25--4911
TIA1--4929
RBM15B--5931
JMJD6--7161
CELF1--7554
RBM4--8366
HNRNPH1--9630
MBNL3--10153
SRSF6--10440
RPS26--111961
RBM38--12396
U2AF2--17548
FASTK0.25120951
HNRNPLL--21130
NSRP1--21617
CWC22--22842
HNRNPF--22937
ESRP1--23503
ESRP2--23938
RPS13--25421

Network

GO:0043484

Network
Enrichment
NameDescriptionExternal IDs
AFF2AF4/FMR2 family, member 2 Entrez:2334  HGNC: 3776  HPRD: 02397  Ensembl: ENSG00000155966 
TRA2Btransformer 2 beta homolog (Drosophila) Entrez:6434  HGNC: 10781  HPRD: 04097 
SONSON DNA binding protein Entrez:6651  HGNC: 11183  Ensembl: ENSG00000159140  HPRD: 01678 
DDX5DEAD (Asp-Glu-Ala-Asp) box helicase 5 Entrez:1655  HPRD: 01615  Ensembl: ENSG00000108654  HGNC: 2746 
PTBP1polypyrimidine tract binding protein 1 Entrez:5725  HGNC: 9583  Ensembl: ENSG00000011304  HPRD: 02823 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AFF2AF4/FMR2 family, member 2
TRA2Btransformer 2 beta homolog (Drosophila)
SONSON DNA binding protein
DDX5DEAD (Asp-Glu-Ala-Asp) box helicase 5
PTBP1polypyrimidine tract binding protein 1
Query geneGeneGene descriptionEdge score
AFF2AFF2AF4/FMR2 family, member 2
TRA2BTRA2Btransformer 2 beta homolog (Drosophila)
SONSONSON DNA binding protein
DDX5DDX5DEAD (Asp-Glu-Ala-Asp) box helicase 5
PTBP1PTBP1polypyrimidine tract binding protein 1

Troyanskaya Laboratory - Princeton University