ASD: Genome-wide prediction of autism-associated genes

Gene	Input weight	Standard	Rank
CNR1	0.25	1	10
GRIN2A	0.25	1	56
SLC6A1	0.25	1	238
DRD5	0.25	1	482
GRIN2B	1.0	1	599
DRD1	0.25	1	662
DRD2	0.25	1	2071
DPYSL2	-	-	2131
TACR3	-	-	2526
DRD3	0.25	1	2757
CDK5	0.25	1	3113
PTK2B	-	-	3191
OXTR	0.5	1	4494
ABAT	0.25	1	4838
SLC6A3	0.25	1	5276
HTR1B	0.25	1	5751
ADRA1B	0.25	1	5964
DRD4	0.25	1	7058
SLC18A2	-	-	7407
OXT	0.25	1	10022
HNMT	-	-	13018
CHRNB2	0.25	1	20277
SMPD1	-	-1	24037

Network

GO:0042220

Minimum relationship confidence:

Maximum number of genes:

Name	Description	External IDs
CNR1	cannabinoid receptor 1 (brain)	Entrez:1268 HGNC: 2159 Ensembl: ENSG00000118432 HPRD: 00259
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	Entrez:2903 HGNC: 4585 Ensembl: ENSG00000183454 HPRD: 00698
SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1	Entrez:6529 Ensembl: ENSG00000157103 HGNC: 11042 HPRD: 00664
DRD5	dopamine receptor D5	Entrez:1816 HGNC: 3026 Ensembl: ENSG00000169676 HPRD: 00542
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	Entrez:2904 Ensembl: ENSG00000150086 HPRD: 00697 HGNC: 4586

Geneset	Type	Freq. (Network vs Genome)	P-Value (FDR Corrected)	Genes

Gene	Description	Avg. edge score to query	Rank	In geneset	In query
CNR1	cannabinoid receptor 1 (brain)
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1
DRD5	dopamine receptor D5
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Query gene	Gene	Gene description	Edge score
CNR1	CNR1	cannabinoid receptor 1 (brain)
GRIN2A	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
SLC6A1	SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1
DRD5	DRD5	dopamine receptor D5
GRIN2B	GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B