ASD

GO:0032147 activation of protein kinase activity (148)

GeneInput weightStandardRank
GAP43--29
YWHAB0.25145
ADNP0.5191
ADCY2--102
KRAS--1143
GRM50.251196
NRG10.251285
CALCA--460
ADCY10.251466
MAP2K10.251474
ADORA1--498
GRM10.251523
PRKACB--544
TGFB2--625
DGKZ--725
DGKI--807
CHRNA3--910
PRLR0.251955
MAPK1--985
MAP2K20.2511066
DGKB--1122
PRKAR1B--1163
CARTPT0.2511181
MAP3K5--1245
KIDINS220--1337
PRKAR2B--1512
TNIK--1544
ADRA2A0.2511556
DGKG--1661
CCK0.2511662
PRKAR1A--11718
ADCY8--1906
DRD20.2512071
MAP3K7--2169
ZFP91--2271
FLT10.2512278
ADCY9--2435
TAOK20.2512490
MAP3K13--2868
WNT5A--2870
SPECC1L--3048
ACVR2B--13179
PTK2B--3191
EDNRA--13271
PRKACG--3335
ANGPT1--3376
MAPKBP1--3672
NGF0.2513749
PDPK1--4150
ADCY5--4352
ADCY6--4362
ITGB30.514442
CRK--4478
ADCY3--4618
NTRK10.2514883
DGKE--4906
BMP4--15180
HTR2B--5233
PARD3--5406
NRAS--15506
RAF10.2515559
HTR1B0.2515751
CCDC88A--5761
IL2--5825
GADD45B--6021
TGFBR1--16027
MAPK30.2516096
TNFSF15--6158
DGKD--6199
GNAI2--6384
ADRA2C--6524
MAP3K4--6590
CHRM1--6680
CERK--6698
MAP3K1--16751
SPHK2--6952
HCRT0.2517434
PLCE1--7692
RAP1A--7718
TLR6--7973
KISS1R--8159
ADRA2B--8196
ADCY4--8354
STRADA--8555
PDGFC--8686
PRKACA--8797
EGF0.2518839
IRAK1--9309
PRKD3--9479
EDN1--9566
ADORA2A0.2519605
RAPGEF1--9624
FGF2--9627
TGFBR2--19756
TAB1--9783
DGKH--9885
GHR--110058
MS4A2--10551
DLG1--10557
CERKL--110893
AXIN1--110905
INSR--110986
PICK1--11571
GADD45G--11613
LAMTOR2--11829
BDKRB1--11977
PDGFB--12484
F2R--12498
FRS2--12610
BRAF--112672
DGKQ--12728
HRAS0.25112845
TNFRSF10B--12951
LRRK2--113335
EDN2--13347
CARD14--13915
AZU1--14133
MALT1--14761
TRAF6--14847
DGKK--16510
PILRB--17723
INS--119021
AGK--19080
TNF0.25119823
SLC11A1--19965
JAK2--120033
PSEN1--20241
TLR3--20315
TRAF7--21105
PRKAR2A--21408
SPHK1--21548
TNFRSF10A--21606
STRADB--21620
MAP4K1--22293
CLSPN--22424
CARD10--22698
ADRB20.25122718
LRP1--22904
MAP3K11--23341
DGKA--23509
TRAF2--23633
IKBKG--123817
CDK1--24001
ANG--124265
ADAM9--124801
PPAP2A--25039
ADCY7--25198
TPX2--25619

Network

GO:0032147

Network
Enrichment
NameDescriptionExternal IDs
GAP43growth associated protein 43 Entrez:2596  Ensembl: ENSG00000172020  HPRD: 01198  HGNC: 4140 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GAP43growth associated protein 43
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ADNPactivity-dependent neuroprotector homeobox
ADCY2adenylate cyclase 2 (brain)
KRASKirsten rat sarcoma viral oncogene homolog
Query geneGeneGene descriptionEdge score
GAP43GAP43growth associated protein 43
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ADNPADNPactivity-dependent neuroprotector homeobox
ADCY2ADCY2adenylate cyclase 2 (brain)
KRASKRASKirsten rat sarcoma viral oncogene homolog

Troyanskaya Laboratory - Princeton University