ASD

GO:0010817 regulation of hormone levels (192)

GeneInput weightStandardRank
SNAP250.2516
NEUROD1--1136
PCSK2--153
MEG3--201
CACNA1A--1231
PDGFRA--1233
RIMS2--273
YWHAZ0.251282
CRH--328
DIO2--434
NR3C1--463
PCSK1--604
RAPGEF40.251635
PCSK6--731
SCHIP1--738
LRP20.251745
SCG50.251824
CAMK2G--925
YWHAH--1109
CARTPT0.2511181
VGF0.2511243
CYP26B1--1419
TSHB--1503
EDN3--11522
FZD4--11666
FKBP1B--1700
PCSK1N--1738
CPE--1784
ESR10.2511914
CGA0.2511927
CRHBP--1966
GHSR0.2512085
RBP4--2097
CYP26A1--2181
FOXA1--2277
GHRHR--2312
ASMTL--2741
CPLX1--2921
CRYM--2922
DIO3--3077
CYP17A10.2513171
ACVR2B--13179
FOXE3--13264
MC4R0.2513280
CYP19A10.2513314
FOXE1--13384
HSD3B2--3449
ALDH1A2--3466
SRD5A20.2513657
SRD5A10.2513730
NGF0.2513749
AGT--13783
TPO--13804
HSD11B10.2513814
CORIN--3841
TBX3--3843
STAT5B--3888
CPLX3--3906
CACNA1H1.013918
TIPARP--4069
TPH20.2514182
CHST8--4221
SLC5A5--14240
PRLHR--4322
ADH7--4488
CYP11A10.2514559
GHRH--4568
IL6--14578
SAFB--4614
RDH12--14638
AKR1D1--14697
SOX8--4770
FURIN--4868
LRAT--14885
DBH0.2514946
HSD3B1--4962
PNMT--5060
CYP1A10.2515095
HNF1A--15114
DDC0.2515222
LYN--5289
ASMT0.2515574
SLC30A8--15810
STAR--5840
CHST9--5987
SDR16C5--5989
SULT1E1--6029
TPH10.2516110
UGT1A8--6303
HSD17B6--6349
AANAT0.2516439
RBP1--6458
TH0.2516482
CYP11B10.2516525
MED1--6574
REN--16631
ALDH8A1--6657
SHBG0.2516818
CYP26C1--6885
ECE2--6886
SMAD2--7224
CYP21A20.2517267
DHRS2--7298
SLC18A2--7407
GCNT4--7454
ANXA1--7465
CCKAR--7616
AKR1C4--7675
HSD17B30.2517714
DUOX1--7758
AKR1B10.2517955
DIO1--8014
FSHB0.2518120
RDH8--8227
AFP--8347
PDX1--18378
SULT1B1--8414
CYP3A4--8506
SERPINA6--8716
BCO2--9015
LY6E--9169
ACE--9212
KLK6--9270
GHRL0.2519333
HNF1B--19562
EDN1--9566
RDH10--9600
GAL--9612
FGF2--9627
INHBA--9731
DUOX2--19797
FAM3B--9848
COMT0.2519945
ADH4--10039
IYD--10193
ACE2--10229
FFAR4--10349
CGB7--10603
UGT2B4--10615
HSD11B2--10731
ADM--10761
SLC22A1--11144
CYP11B2--11354
SCARB1--11598
PLEKHA1--11683
SLCO4A1--12009
PCSK5--12160
TG--12189
DHRS9--12752
POMC0.25112902
CGB8--12913
GPR119--13231
LEP0.25113368
LHB0.25113521
UGT1A9--13900
CYB5R4--14019
UGT2B11--14046
CGB5--14742
MAFA--14795
RDH11--14966
UGT1A7--15407
HSD17B20.25115720
ALDH1A3--15783
DGAT1--15809
SHH--115942
EXOC3L1--16762
HSD17B11--17376
CRABP2--17841
SRD5A3--118409
IQCJ-SCHIP1--18546
PCSK7--19604
HSD17B1--19919
EIF2AK3--20407
SGPL1--20483
ECE1--120668
BACE2--21041
CYP1B10.25121393
CGB--21555
STARD5--21575
WNT4--21840
ALDH9A1--21991
UGT1A1--122048
UGT1A3--22349
ATP6AP2--24552
IL1RN0.25124819
DHRS3--25111
LTBP4--25140
RETSAT--25512
SCPEP1--25584
BCAT2--25612
HSD17B8--25637
IDE--25739

Network

GO:0010817

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
PCSK2proprotein convertase subtilisin/kexin type 2 Entrez:5126  Ensembl: ENSG00000125851  HGNC: 8744  HPRD: 01202 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
NEUROD1neuronal differentiation 1
PCSK2proprotein convertase subtilisin/kexin type 2
MEG3maternally expressed 3 (non-protein coding)
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
NEUROD1NEUROD1neuronal differentiation 1
PCSK2PCSK2proprotein convertase subtilisin/kexin type 2
MEG3MEG3maternally expressed 3 (non-protein coding)
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Troyanskaya Laboratory - Princeton University