ASD

GO:0040019 positive regulation of embryonic development (7)

GeneInput weightStandardRank
PLCB1--161
MEG3--201
AMOT--933
OTX2--11295
FOXA2--1835
LHX1--1926
RBM19--10966

Network

GO:0040019

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
AMOTangiomotin Entrez:154796  HGNC: 17810  Ensembl: ENSG00000126016  HPRD: 02327 
OTX2orthodenticle homeobox 2 Entrez:5015  HGNC: 8522  HPRD: 07190  Ensembl: ENSG00000165588 
FOXA2forkhead box A2 Entrez:3170  HGNC: 5022  Ensembl: ENSG00000125798  HPRD: 02618 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3maternally expressed 3 (non-protein coding)
AMOTangiomotin
OTX2orthodenticle homeobox 2
FOXA2forkhead box A2
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3MEG3maternally expressed 3 (non-protein coding)
AMOTAMOTangiomotin
OTX2OTX2orthodenticle homeobox 2
FOXA2FOXA2forkhead box A2

Troyanskaya Laboratory - Princeton University