ASD

GO:0001708 cell fate specification (48)

GeneInput weightStandardRank
NTRK30.2514
SOX2--1125
ASCL1--229
POU4F1--292
PAX60.251355
OLIG2--420
PAX2--459
NKX2-2--771
SOX9--11045
ISL1--1441
FOXA2--1835
SOX6--1939
NODAL--12184
FOXA1--2277
HOXD10--2845
NKX6-1--3174
NOTCH1--13360
CDON--3482
SOX17--3484
HOXA13--3602
HOXA11--4215
ITGB1--4390
EYA2--4403
HOXC10--4404
NANOG--4730
IHH--14742
PRDM14--5341
LBX1--5371
NKX6-2--5422
FOXI1--15442
TLX3--5583
GLI2--15731
MNX1--5932
CTNNB10.2516229
GSX2--6242
MYL2--16261
SIX2--6713
GLI3--19032
ATOH1--9258
FOXA3--9582
EVX1--12405
FOXI2--12798
SHH--115942
FOXI3--17045
PSEN1--20241
POU5F1--21422
PSEN2--21431
TEAD4--25169

Network

GO:0001708

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
POU4F1POU class 4 homeobox 1 Entrez:5457  Ensembl: ENSG00000152192  HGNC: 9218  HPRD: 03379 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
SOX2SRY (sex determining region Y)-box 2
ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU class 4 homeobox 1
PAX6paired box 6
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
SOX2SOX2SRY (sex determining region Y)-box 2
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU4F1POU class 4 homeobox 1
PAX6PAX6paired box 6

Troyanskaya Laboratory - Princeton University