ASD

GO:0009187 cyclic nucleotide metabolic process (48)

GeneInput weightStandardRank
ATP2B20.511
HTR2C0.25146
ADCY2--102
PDE8B--1323
PDE4D--357
ADCY10.251466
GUCY1B3--560
GNAL--860
PDE4A--1000
PTHLH--11269
PDE2A--1591
GUCY1A2--1629
GUCY1A3--1730
PDE4B--1754
PDE1B--1791
ADCY8--1906
PDE11A--2107
ADCY10--2222
GNAS--12352
ADCY9--2435
PDE3A--3024
PDE3B--3088
GUCY2F--3945
PDE4C--4298
ADCY5--4352
ADCY6--4362
ADCY3--4618
NUDT4--5056
GUCY2D--15204
HTR2B--5233
PTH--5481
NPPB--5967
NPR2--16150
RORA--6355
NPPC--7442
GUCY2C--8098
PDE5A--8315
ADCY4--8354
GUCA2B--8899
PDE8A--9552
ADORA2A0.2519605
UCN2--9660
NPPA--110598
ADM--10761
CNP--17352
AQP1--21019
NPR1--24360
ADCY7--25198

Network

GO:0009187

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
PDE8Bphosphodiesterase 8B Entrez:8622  HGNC: 8794  Ensembl: ENSG00000113231  HPRD: 04546 
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ADCY2adenylate cyclase 2 (brain)
PDE8Bphosphodiesterase 8B
PDE4Dphosphodiesterase 4D, cAMP-specific
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ADCY2ADCY2adenylate cyclase 2 (brain)
PDE8BPDE8Bphosphodiesterase 8B
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific

Troyanskaya Laboratory - Princeton University