ASD

GO:0030517 negative regulation of axon extension (13)

GeneInput weightStandardRank
SLIT1--33
BCL11A--44
SEMA4F--179
RTN4--1776
NRP1--1961
SEMA3A--2076
TNR--2784
WNT5A--2870
RNF6--14587
WNT3--4799
WNT3A--4844
NTN1--5275
RYK--12768

Network

GO:0030517

Network
Enrichment
NameDescriptionExternal IDs
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) Entrez:53335  Ensembl: ENSG00000119866  HGNC: 13221  HPRD: 05949 
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F Entrez:10505  HGNC: 10734  HPRD: 04748 
RTN4reticulon 4 Entrez:57142  Ensembl: ENSG00000115310  HGNC: 14085  HPRD: 07259 
NRP1neuropilin 1 Entrez:8829  HGNC: 8004  Ensembl: ENSG00000099250  HPRD: 03642 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLIT1slit homolog 1 (Drosophila)
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
RTN4reticulon 4
NRP1neuropilin 1
Query geneGeneGene descriptionEdge score
SLIT1SLIT1slit homolog 1 (Drosophila)
BCL11ABCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
SEMA4FSEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
RTN4RTN4reticulon 4
NRP1NRP1neuropilin 1

Troyanskaya Laboratory - Princeton University