ASD

GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome (15)

GeneInput weightStandardRank
TRA2B--65
DDX5--506
PTBP1--583
CELF3--607
MBNL1--1113
RBM5--1665
CELF4--1983
MYOD1--2280
RBMX--2432
SRSF12--2655
CELF6--3255
RBM25--4911
RBM15B--5931
RBM4--8366
NSRP1--21617

Network

GO:0000381

Network
Enrichment
NameDescriptionExternal IDs
TRA2Btransformer 2 beta homolog (Drosophila) Entrez:6434  HGNC: 10781  HPRD: 04097 
DDX5DEAD (Asp-Glu-Ala-Asp) box helicase 5 Entrez:1655  HPRD: 01615  Ensembl: ENSG00000108654  HGNC: 2746 
PTBP1polypyrimidine tract binding protein 1 Entrez:5725  HGNC: 9583  Ensembl: ENSG00000011304  HPRD: 02823 
CELF3CUGBP, Elav-like family member 3 Entrez:11189  HGNC: 11967  HPRD: 18210 
MBNL1muscleblind-like splicing regulator 1 Entrez:4154  Ensembl: ENSG00000152601  HGNC: 6923  HPRD: 07355 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TRA2Btransformer 2 beta homolog (Drosophila)
DDX5DEAD (Asp-Glu-Ala-Asp) box helicase 5
PTBP1polypyrimidine tract binding protein 1
CELF3CUGBP, Elav-like family member 3
MBNL1muscleblind-like splicing regulator 1
Query geneGeneGene descriptionEdge score
TRA2BTRA2Btransformer 2 beta homolog (Drosophila)
DDX5DDX5DEAD (Asp-Glu-Ala-Asp) box helicase 5
PTBP1PTBP1polypyrimidine tract binding protein 1
CELF3CELF3CUGBP, Elav-like family member 3
MBNL1MBNL1muscleblind-like splicing regulator 1

Troyanskaya Laboratory - Princeton University